流感样病例定义对流感监测结果影响的比较分析

发布时间：2018-03-17 08:35

  本文选题：流感　切入点：人　出处：《中华疾病控制杂志》2017年09期 　论文类型：期刊论文

【摘要】：目的比较不同临床症状的流感样病例流感检出情况的差异,探讨采用不同流感样病例定义对流感监测结果的影响。方法根据2015年上海市2家国家级流感监测哨点医院的流感病原学监测数据和病例临床症状,计算不同临床症状(有咳嗽咽痛、仅咳嗽、仅咽痛)的流感样病例流感病毒检出情况,并通过多因素Logistic回归分析流感病毒检出情况的影响因素。结果 2 010例流感样病例中,有咳嗽咽痛者1 105例、仅有咳嗽者270例、仅有咽痛者635例,流感阳性率分别为36.2%、39.3%和15.9%,经分析,有咳嗽咽痛者、仅有咳嗽者的流感阳性检出率均高于仅有咽痛者(均有P0.05)。对于发病3 d内采样的流感样病例,有咳嗽咽痛、仅有咳嗽者的流感阳性检出率均高于仅咽痛者(均有P0.05)。多因素Logistic回归分析结果显示,流感病毒检出情况与病例体温(≥39℃)(OR=1.719,95%CI:1.389~2.127)、咳嗽(OR=3.046,95%CI:2.377~3.905)有关。结论建议以"发热(体温≥38℃)伴咳嗽症状者"作为流感监测中的流感样病例定义。
[Abstract]:Objective to compare the differences of influenza detection among patients with different clinical symptoms. To explore the effect of different flu-like case definitions on the results of influenza surveillance. Methods according to the data of influenza etiology surveillance and clinical symptoms of two national influenza surveillance sentinel hospitals in Shanghai in 2015. The detection of influenza virus in patients with different clinical symptoms (cough and pharynx, cough only and pharynx only) was calculated, and the influencing factors of influenza virus detection were analyzed by multivariate Logistic regression analysis. There were 1 105 cases with cough and pharynx, 270 cases with cough and 635 cases with sore throat. The positive rates of influenza were 39.3% and 15.9%, respectively. The positive rate of influenza in patients with cough was higher than that in patients with pharynx (P 0.05). The positive rate of influenza in patients with cough was higher than that in patients with pharynx only (P 0.05). Multivariate Logistic regression analysis showed that, The detection of influenza virus is related to the body temperature of the case (鈮，

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