颚口线虫病16例流行病学及临床特征分析

发布时间：2018-03-24 08:20

本文选题：颚口线虫病　切入点：流行病学　出处：《中国人兽共患病学报》2017年11期

【摘要】：目的探讨我国新发颚口线虫病的流行病学、临床表现等特征。方法回顾性分析2009—2011年间16例新发颚口线虫病的相关资料。结果 16例病人中,女性11例,男性5例,年龄27~68岁,中位年龄48岁;68.8%(11/16)病人有食生的或半生淡水鱼史。临床表现以移走性皮下包块、匍行疹、皮疹等为主,43.8%(7/16)病人外周血嗜酸性粒细胞异常增高。16例病人血清用金标免疫渗滤法检测特异性IgG抗体均阳性,用免疫印迹检测5例(31.2%)阳性;病程2周~3年不等,平均12个月;11例病人口服伊维菌素和/或阿苯达唑治疗,10例完全治愈。结论生食或半生食泥鳅等淡水鱼导致颚口线虫病病例明显上升;该病容易误诊、漏诊,血清学检测是临床上必不可少的辅助诊断工具;伊维菌素、阿苯达唑治疗颚口线虫病具有较好疗效。
[Abstract]:Objective to investigate the epidemiological and clinical features of newly diagnosed maxillary nematode disease in China. Methods the data of 16 patients with newly diagnosed maxillary nematode from 2009 to 2011 were analyzed retrospectively. Results among the 16 patients, 11 were female and 5 were male, aged 2768 years. The median age of 48 years was 68. 8% and 11 / 16) the patient had a history of fresh or semi-born freshwater fish. The clinical manifestations were as follows: removal of subcutaneous mass, creeping rash, Peripheral eosinophilic granulocytes were abnormally elevated in 16 patients. The serum of 16 patients was positive for specific IgG antibodies by gold labeled immunofiltration, and 5 patients were positive by Western blotting. The course of disease ranged from 2 weeks to 3 years, the course of disease ranged from 2 weeks to 3 years, the course of disease ranged from 2 weeks to 3 years, the course of disease ranged from 2 weeks to 3 years. An average of 11 patients were treated with ivermectin and / or albendazole for 12 months, 10 patients were cured completely. Conclusion fresh fish such as raw or semi raw feeding Loach lead to a significant increase in cases of maxillary nematode disease, the disease is easy to be misdiagnosed and missed diagnosis. Serological examination is an indispensable tool for clinical diagnosis, and ivermectin and albendazole are effective in the treatment of maxillary nematode disease.
【作者单位】：浙江省医学科学院寄生虫病研究所;
【分类号】：R181.3;R532.1

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