恶性肿瘤患者医院感染危险因素分析

发布时间：2018-03-29 12:43

本文选题：恶性实体肿瘤　切入点：医院感染　出处：《中华医院感染学杂志》2014年10期

【摘要】：目的探讨恶性实体肿瘤患者医院感染危险因素,为临床中预防恶性实体肿瘤发生医院感染提供参考依据。方法对医院2010年1月-2012年12月收录的200例恶性实体肿瘤患者的临床资料进行回顾性分析,探讨发生医院感染的危险因素。结果 200例恶性实体肿瘤患者中有12例发生医院感染,感染率为6.0%;感染部位以下呼吸道、皮肤软组织、上呼吸道为主,分别占33.3%、25.0%、16.7%;共培养出病原菌20株,排名前3位病原菌依次为假单胞菌属、大肠埃希菌和金黄色葡萄球菌,分别占25.0%、20.0%、20.0%;logistic回归分析结果显示,住院时间、临床分期、化疗与放疗、侵入性操作、抗菌药物使用、伴有糖尿病和肿瘤转移是恶性实体肿瘤患者发生医院感染的危险因素(P0.05)。结论临床中恶性实体肿瘤患者很容易诱发医院感染,影响因素也比较多,临床中应加强针对性的干预,从而有效降低感染的发生。
[Abstract]:Objective to investigate the risk factors of nosocomial infection in patients with malignant solid tumors. Methods the clinical data of 200 patients with malignant solid tumors collected from January 2010 to December 2012 were analyzed retrospectively. Results 12 out of 200 patients with malignant solid tumor had nosocomial infection, and the infection rate was 6.0. 20 strains of pathogenic bacteria were cultured, among which the top 3 pathogens were Pseudomonas, Escherichia coli and Staphylococcus aureus respectively. The results of logistic regression analysis showed that hospital stay, clinical stage, chemotherapy and radiotherapy were the main causes of the disease, and the results of logistic regression analysis showed that the first three pathogens were Pseudomonas, Escherichia coli and Staphylococcus aureus, respectively. Invasive operation, antibiotic use, diabetes mellitus and tumor metastasis are the risk factors for nosocomial infection in patients with malignant solid tumors. Conclusion it is easy to induce nosocomial infection in patients with malignant solid tumors in clinic, and there are many influencing factors. Clinical intervention should be strengthened to effectively reduce the incidence of infection.
【作者单位】：都匀市州人民医院肿瘤科;
【基金】：高等学校博士学科点专项科研基金项目(200804871030)
【分类号】：R181.32

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