贵州省含麻疹成分疫苗免疫失败麻疹病例流行病学特征研究

发布时间：2018-04-29 15:50

本文选题：麻疹 + 含麻疹成分疫苗　；参考：《中国疫苗和免疫》2017年05期

【摘要】：目的分析贵州省含麻疹成分疫苗(MCV)免疫失败麻疹病例的流行病学特征。方法对2010-2015年麻疹监测报告信息管理系统中麻疹病例个案资料进行收集整理,采用描述性流行病学法分析。结果 2010-2015年贵州省报告MCV免疫失败麻疹病例88例,占麻疹病例总数的13.15%。免疫失败病例分布在全省8个市(州)35个县,各市(州)免疫失败病例在麻疹总病例中构成比在0.00%(铜仁)-20.75%(黔南)之间(χ~2=33.96,P=0.000);各年龄组在7.23%(14岁)-34.28%(2-6岁)之间(χ~2=44.89,P=0.000)。免疫失败病例与麻疹总病例的月分布一致(r=0.74,P=0.006)。接种过1剂次、≥2剂次MCV的免疫失败病例分别占59.09%、40.91%。结论贵州省MCV免疫失败病例在麻疹病例中占一定比例,需进一步提高MCV预防接种质量。
[Abstract]:Objective to analyze the epidemiological characteristics of measles cases with measles vaccine MCV immunization failure in Guizhou province. Methods the data of measles cases in the information management system of measles surveillance report from 2010 to 2015 were collected and analyzed by descriptive epidemiology. Results 88 measles cases with MCV immunization failure were reported in Guizhou province from 2010 to 2015, accounting for 13.15% of the total measles cases. Immunization failure cases were distributed in 35 counties in 8 cities (prefectures) of the province, and the proportion of the total measles cases in each city (prefecture) was 0.005 (Tongren -20.75) (蠂 ~ (2 +) 33.96) (蠂 ~ (2) 2) 33.96 (P ~ (0.000), and the age group was between 7.23 ~ (14) years -34.28 ~ (2) 2-6 years old (蠂 ~ (24) 44.89) ~ (0.000). The monthly distribution of immunization failure cases and total measles cases were identical. The cases of immune failure with one dose or more than 2 doses of MCV accounted for 59.09% and 40.91% respectively. Conclusion MCV immunization failure is a certain proportion of measles cases in Guizhou Province, and the quality of MCV vaccination should be further improved.
【作者单位】：贵州省疾病预防控制中心;
【分类号】：R181.3;R511.1

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