新生儿病区医院感染危险因素分析

发布时间：2018-05-31 07:05

本文选题：新生儿 + 医院感染　；参考：《中华医院感染学杂志》2014年20期

【摘要】：目的研究新生儿医院感染的相关危险因素,为临床控制感染提供依据。方法采用回顾性调查方法对2010年1月-2013年12月新生儿病区2 161例患儿临床资料进行分析,应用单因素卡方、多因素回归进行统计分析。结果共有70例新生儿发生医院感染,感染率为3.24%,主要病原菌包括凝固酶阴性葡萄球菌19株、屎肠球菌6株、酿脓链球菌4株,分别占34.4%、10.9%、7.3%;单因素分析结果显示,高危新生儿、新生儿窒息、高胆红素血症、肺炎、早产、低体质量儿、性别、总住院天数、新生儿病区住院天数、中心静脉置管、使用呼吸机与医院感染的发生存在密切的相关性(P0.05);多因素分析结果显示,高危新生儿、高胆红素血症、肺炎、早产、总住院天数多、新生儿病区住院天数长、使用呼吸机是感染发生的独立危险因素(P0.05)。结论在临床工作中,针对高危新生儿、高胆红素血症、肺炎、早产、住院时间长的患儿加强关注,控制呼吸机的使用可降低感染的发生。
[Abstract]:Objective to study the risk factors of nosocomial infection in neonates and to provide evidence for clinical control of nosocomial infection. Methods the clinical data of 2 161 neonates in neonatal ward from January 2010 to December 2013 were analyzed retrospectively. Single factor chi-square and multivariate regression were used to analyze the clinical data. Results A total of 70 neonates had nosocomial infection, the infection rate was 3.24. The main pathogens included 19 coagulase negative staphylococci, 6 Enterococcus faecium and 4 Streptococcus pyogenes, accounting for 34.4% 10.9% and 7.3% respectively. Neonatal asphyxia, hyperbilirubinemia, pneumonia, premature delivery, low body mass infant, sex, total hospital stay, hospital stay in neonatal ward, central venous catheterization, The results of multivariate analysis showed that high risk neonates, hyperbilirubinemia, pneumonia, premature delivery, more days of total hospitalization and long hospitalization days of neonates were found. Ventilator is an independent risk factor for infection. Conclusion in clinical work, attention should be paid to high risk neonates, hyperbilirubinemia, pneumonia, premature delivery and long hospital stay, and the use of ventilator can reduce the incidence of infection.
【作者单位】：潍坊医学院公共卫生学院;解放军总医院感染管理与疾病控制科;
【基金】：国家自然科学基金资助项目(30872155) 国家科技重大专项基金资助项目(2013ZX 10004805-003) 全军医学科技“十二五”科研基金资助项目(AWS11L009、11BJZ01)
【分类号】：R181.32

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