洪江市部分地区儿童青少年臀肌挛缩症流行病学调查

发布时间：2018-06-07 04:21

本文选题：儿童臀肌挛缩症 + 流行病学　；参考：《中南大学》2010年硕士论文

【摘要】： [目的]了解儿童臀肌挛缩症(gluteal muscle contracture,GMC)在湖南省西部地区发病率情况并对其相关致病危险因素进行分析。比较该地区于2000年停止使用2%苯甲醇做臀部肌肉注射溶剂前后出生的儿童青少年患病率情况。 [方法]2009年10月对湖南省洪江市部分中小学校4-17岁的2000余名儿童和青少年进行普查。制定臀肌挛缩流行病学调查表(见附表),2009年10月10-11日组织本专业执行调查的医务人员4人进行培训,统一调查项目的评定标准,10月12-23日到洪江市两所小学和两所中学展开调查。调查分问卷调查和体格检查两个方面,调查步骤包括：第一步发放问卷调查表了解①一般情况：姓名、性别、年龄、名族、住址、电话。②既往史：臀肌注射史,外伤史。③体查：将臀肌挛缩的体查分为轻度、中度、重度三级：轻度仅在臀部可见到皮肤凹陷或可扪及硬结和条索状物,髋关节活动不受限制；中度为髋关节活动受到一定限制但无畸形,表现为步态异常,八字步态,摇摆步态,跛行,髋部弹响,不能跷二郎腿,并膝下蹲时分膝或下蹲困难,或者下蹲时双足后跟离地；重度表现为骨盆倾斜,相对双下肢不等长,脊柱侧弯等畸形。第二步,对有阳性体征的调查对象抽出后,通过电话联系其家长,详细了解相关情况：注射原因、初次注射年龄、注射次数、外伤史情况、发病年龄、家族遗传史等。第三步,走访调查学校所在的卫生机构,明确用于臀肌注射的常用药物种类、配伍、注射及消毒的方法。调查完成以后将统计资料统一编码,应用SPSS 11.5统计学软件输入后进行单因素分析,运用卡方检验和多因素条件logistic回归分析方法,筛选出有意义的危险因素。 [结果]本研究实际调查4-17岁儿童青少年2067名,男1058人占51.43%,女1009人占48.82%,100%有臀部肌肉注射史。929名4-9岁(即2000年以后出生)的儿童发病人数为205人,发病率为22.07%(205／929),其中男性发病率22.95%(109／475),女性发病率为21.15%(96／454),体查发现臀肌轻度挛缩的155人,占16.68%(155／929),中、重度挛缩的有50人,占5.38%(50／929)。1138名10-17岁(2000年以前出生)的男性583人占51.23%,女性555人占48.77%,体查有阳性体征的人数为327人,发病率为28.73%(327／1138),其中男性发病率30.87%(180／583),女性发病率26.49%(147／555),体查发现轻度臀肌挛缩的有209人占18.37%(209／1138),中、重度臀肌挛缩的118人,占10.37%(118／1138)。 [结论]湖南省洪江市部分地区4-17岁儿童青少年臀肌挛缩症总体发病率为25.74%,其中轻度挛缩的占17.61%,中、重度以上挛缩的占8.13%,初步了解了湖南省洪江市儿童青少年臀肌挛缩症症流行病现状及主要的致病原因,为进一步了解臀肌挛缩症的发病原因制定标准化的防治措施提供流行病学资料。
[Abstract]:Objective : To investigate the prevalence of breech muscle contracture of children in western Hunan and to analyze the related risk factors . The prevalence of children and adolescents born before and after the use of 2 % benzyl alcohol in the region was stopped in 2000 .

In October 2009 , 2000 children and adolescents from 4 to 17 years of age in Hongjiang city of Hunan Province were investigated . The epidemiological survey of gluteus muscle contracture was established ( see attached table ) , and the investigation was conducted in two primary schools and two schools in Hongjiang City on Oct . 10 - 11 , 2009 .
Moderate to hip joint activity is limited but not deformity , manifested as gait abnormality , eight - step gait , swing gait , lameness , hip pop , can ' t have two Lang ' s legs , and knees squatting on the knees or squatting difficult , or when squatting on the feet and out of ground ;
In the second step , after the investigation objects with positive signs were extracted , the parents were contacted by telephone to learn more about the related situation : the causes of injection , the age of the primary injection , the number of injections , the history of trauma , the age of the onset , the history of family heredity , etc . The third step , after the investigation was completed , the statistical data were unified and coded .

Results : The incidence rate of female children aged from 4 to 9 years ( birth in 2000 years ) was 5.38 % ( 205 / 929 ) . Among them , the incidence rate was 22.07 % ( 205 / 929 ) . Among them , the incidence rate was 30.87 % ( 180 / 583 ) .

Conclusion The overall incidence of gluteus contracture of children aged 4 - 17 in Hongjiang City , Hunan Province is 25.74 % . Among them , the prevalence of mild contracture is 17.61 % . In the middle and severe contracture accounts for 8.13 % , the present status and main causes of the epidemic diseases among children and adolescents in Hongjiang city of Hunan Province are preliminarily understood , and the epidemiological data is provided for further understanding the causes of gluteus contracture .
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R685;R181.3

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