环氧乙烷灭菌与压力蒸汽灭菌对含银敷料白度及抗菌活性影响研究

发布时间：2018-06-29 06:57

本文选题：含银敷料 + 灭菌方法　；参考：《中华医院感染学杂志》2014年20期

【摘要】：目的探讨环氧乙烷灭菌与高温高压蒸汽灭菌对含银敷料白度及抗菌活性的影响,以确保含银敷料灭菌后可以保持其正常的白度及抗菌活性。方法将20份含银敷料分为环氧乙烷灭菌前后组和高温高压蒸汽灭菌前后组,每组各5份;利用测色配色仪测试敷料白度变化;采用平皿扩散法观察经过两种灭菌方法的含银辅料各自对金黄色葡萄球菌和大肠埃希菌的抗菌活性,通过测量抑菌带宽度,评价含银敷料的抗菌能力。结果含银敷料经高温高压蒸汽灭菌后白度从58.34下降至-64.17,环氧乙烷灭菌前敷料的白度值为58.34,灭菌后为57.35,白度基本不变;抗菌活性试验结果显示,两种灭菌方法不影响含银敷料的抗菌活性;环氧乙烷灭菌敷料对金黄色葡萄球菌和大肠埃希菌的抑菌带宽分别为2.0、0.9mm,高温高压蒸汽灭菌敷料对金黄色葡萄球菌和大肠埃希菌抑菌带宽分别为1.9、0.5mm。结论采用环氧乙烷灭菌法对含银敷料灭菌能够更好地保持敷料原有的白度和抗菌功能。
[Abstract]:Objective to study the effect of ethylene oxide sterilization and high temperature and high pressure steam sterilization on the whiteness and antibacterial activity of silver dressing, so as to ensure the normal whiteness and antibacterial activity of silver dressing. Methods 20 samples of silver dressing were divided into two groups: before and after ethylene oxide sterilization and before and after high temperature and high pressure steam sterilization, each group was divided into 5 parts, and the whiteness of dressing was measured by colorimetric colorimeter. The antibacterial activities of silver containing excipients against Staphylococcus aureus and Escherichia coli were observed by plate diffusion method. The antibacterial ability of silver containing dressings was evaluated by measuring the width of bacteriostasis band. Results the whiteness of silver dressing decreased from 58.34 to -64.17 after sterilizing by high temperature and high pressure steam. The whiteness of dressing before and after sterilization was 58.34 and 57.35 respectively. The antibacterial activity of silver dressing was not affected by two sterilization methods. The inhibition bandwidth of ethylene oxide sterilization dressing on Staphylococcus aureus and Escherichia coli was 2.0 ~ 0.9mm, respectively, and that of high-temperature and high-pressure steam sterilization dressing on Staphylococcus aureus and Escherichia coli was 1.9 ~ 0.5mm. Conclusion the sterilization of silver dressing by ethylene oxide sterilization can better maintain the whiteness and antibacterial function of the dressing.
【作者单位】：武警后勤学院附属医院消毒供应中心;武警后勤学院附属医院护理部;武警后勤学院附属医院化学教研室;
【基金】：武警部队后勤部科研基金资助项目(WJHQ2010-15)
【分类号】：R187.2

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