我国两个农村土壤镉高背景地区非镉职业暴露人群尿镉背景值调查
发布时间：2018-07-15 09:34
【摘要】：目的研究我国农村土壤镉高背景地区非镉职业暴露人群尿镉的正常值范围。方法在非环境镉污染区选择土壤镉高背景区,随机选择各性别及各个年龄段的非镉暴露人群1134人(男性519人,女性615人),进行流行病学调查以及采集随机尿样,检测尿镉及尿肌酐(Cr)含量,剔除Cr浓度0.3 g/L以及3 g/L的调查对象,分析尿镉的影响因素,按95%分位数计算人群经肌酐校正后的尿镉正常值范围。结果女性的尿镉水平显著高于男性,男性吸烟者尿镉水平显著高于男性不吸烟者(P0.05),但P95值相差不大。无论男女,尿镉均值及P95均在15~30岁之间出现低谷,而在15岁以前以及30岁以后出现较高的尿镉负荷。按照15~30岁以及15和≥30岁两个年龄段分析不同性别人群的尿镉上限值,15和≥30岁女性的尿镉均值(4.18μg/gCr)及上限值(12.24μg/gCr)均明显高于其他人群的均值(4μg/gCr)及上限值(9μg/gCr);此外,所调查人群的95%尿镉上限值均超出了我国职业性镉中毒诊断标准(GBZ 17—2002)中的尿镉限值(5μg/gCr)。结论在土壤镉高背景地区,男性尿镉的95%正常值范围9μg/gCr,女性尿镉的95%正常值范围13μg/gCr。
[Abstract]:Objective to study the normal range of urinary cadmium in non-cadmium occupational exposed population in rural areas with high background of soil cadmium. Methods 1134 subjects (519 males and 615 females) were randomly selected from non-cadmium exposed population (male 519, female 615) in the non-environmental cadmium contaminated area, and random urine samples were collected. The contents of urinary cadmium and creatinine (Cr) were detected and the normal range of urinary cadmium after creatinine correction was calculated according to 95 quartiles of urinary cadmium. The subjects with 0.3 g / L Cr and 3 g / L Cr concentration were excluded and the influencing factors of urinary cadmium were analyzed. Results the urinary cadmium level of female was significantly higher than that of male, and that of male smoker was significantly higher than that of male non-smoker (P0.05), but the P95 value was not different. In both men and women, the mean value of urinary cadmium and P95 were low between 15 and 30 years old, and the higher urinary cadmium load appeared before and after the age of 15 years. The upper limit value of urinary cadmium (4.18 渭 g / g Cr) and the upper limit value (12.24 渭 g / g Cr) of 15 and 鈮，
本文编号：2123623
[Abstract]:Objective to study the normal range of urinary cadmium in non-cadmium occupational exposed population in rural areas with high background of soil cadmium. Methods 1134 subjects (519 males and 615 females) were randomly selected from non-cadmium exposed population (male 519, female 615) in the non-environmental cadmium contaminated area, and random urine samples were collected. The contents of urinary cadmium and creatinine (Cr) were detected and the normal range of urinary cadmium after creatinine correction was calculated according to 95 quartiles of urinary cadmium. The subjects with 0.3 g / L Cr and 3 g / L Cr concentration were excluded and the influencing factors of urinary cadmium were analyzed. Results the urinary cadmium level of female was significantly higher than that of male, and that of male smoker was significantly higher than that of male non-smoker (P0.05), but the P95 value was not different. In both men and women, the mean value of urinary cadmium and P95 were low between 15 and 30 years old, and the higher urinary cadmium load appeared before and after the age of 15 years. The upper limit value of urinary cadmium (4.18 渭 g / g Cr) and the upper limit value (12.24 渭 g / g Cr) of 15 and 鈮，
本文编号：2123623
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