某医院骨科住院患者感染病原菌的分布及耐药性研究

发布时间：2018-07-15 16:21

【摘要】：目的研究骨科住院患者感染病原菌种类及其耐药性,为临床合理使用抗菌药物提供参考。方法采用细菌分离培养和药敏试验方法,对某医院骨科病房1 460份送检标本进行细菌鉴定及药敏试验。结果从1 460份标本中共检出病原菌860株,检出率58.9%。在检出的病原菌中,革兰阳性球菌占66.0%,其中金黄色葡萄球菌,表皮葡萄球菌、腐生葡萄球菌居前3位;革兰阴性杆菌占30.0%,主要包括铜绿假单胞菌、大肠埃希菌、鲍曼不动杆菌等;真菌占4.0%。骨科临床分离革兰阳性球菌对万古霉素和替考拉宁敏感,革兰阴性杆菌对亚胺培南敏感。结论骨科住院患者感染病原菌主要是革兰阳性球菌,临床分离的病原菌对常用抗菌药物普遍耐药,根据药敏试验结果选择抗菌药物是有效控制感染的关键。
[Abstract]:Objective to study the types and drug resistance of infectious pathogens in orthopaedic inpatients, and to provide reference for rational use of antimicrobial agents in clinic. Methods bacterial isolation, culture and drug sensitivity test were used to identify 1 460 specimens from orthopaedic ward of a hospital. Results A total of 860 strains of pathogenic bacteria were detected from 1 460 specimens, and the detection rate was 58.9%. Among the pathogens detected, gram-positive cocci accounted for 66.0, among which Staphylococcus aureus, Staphylococcus epidermidis and Staphylococcus saprophyticus ranked the top 3, Gram-negative bacilli accounted for 30.0%, mainly including Pseudomonas aeruginosa and Escherichia coli. Acinetobacter baumannii and so on; fungi account for 4.0. Gram-positive cocci isolated from orthopaedics were sensitive to vancomycin and teicoplanin, and Gram-negative bacilli were sensitive to imipenem. Conclusion Gram-positive cocci are the main pathogens in orthopedic inpatients. The pathogens isolated in clinic are generally resistant to common antimicrobial agents. The key to control infection is to select antimicrobial agents according to the results of drug sensitivity test.
【作者单位】：绍兴市上虞人民医院;
【分类号】：R187

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