鼻咽癌患者医院感染病原菌特点及感染因素分析
发布时间：2018-08-01 18:19
【摘要】：目的探讨鼻咽癌患者医院感染病原菌的特点及引起感染的相关危险因素,以期为鼻咽癌医院感染的防治提供参考依据。方法回顾性分析2001年8月-2012年12月1 123例鼻咽癌住院患者临床资料,数据采用SPSS17.0统计学软件进行统计分析,计数资料采用率表示进行χ2检验,分析病原菌感染特点及相关危险因素。结果共有108例发生医院感染,感染率9.62%,感染部位为口腔黏膜、颈部皮肤、呼吸道、中耳及泌尿道、其他部位,分别占55.56%、21.30%、10.19%、6.48%、2.78%、3.70%;感染部位标本细菌培养结果阳性者97例,阳性率89.81%,检出病原菌106株,其中真菌64株、革兰阴性菌29株、革兰阳性菌13株,其中真菌主要以白色假丝酵母菌为主,占39.62%,革兰阴性菌以铜绿假单胞菌、鲍氏不动杆菌、肺炎克雷伯菌、大肠埃希菌为主,分别占10.38%、6.60%、4.72%、3.77%,革兰阳性菌以金黄色葡萄球菌、溶血性葡萄球菌、表皮葡萄球菌为主,分别占4.72%、2.83%、2.83%;年龄≥65岁、手术治疗、放化疗治疗、抗菌药物使用2种、TNM分期Ⅲ~Ⅳ期、住院时间≥30d的患者是发生医院感染的相关因素。结论鼻咽癌住院患者医院感染病原菌主要为真菌,高龄、手术及放化疗治疗、使用多种抗菌药物、疾病处于中晚期及住院时间长均是引起患者发生医院感染的相关危险因素。
[Abstract]:Objective to investigate the characteristics of nosocomial infection pathogenic bacteria in nasopharyngeal carcinoma (NPC) patients and the risk factors of nosocomial infection in order to provide reference for the prevention and treatment of nasopharyngeal carcinoma nosocomial infection. Methods the clinical data of 1 123 inpatients with nasopharyngeal carcinoma from August 2001 to December 2012 were analyzed retrospectively. The data were statistically analyzed by SPSS17.0 software. The characteristics of pathogenic bacteria infection and related risk factors were analyzed. Results there were 108 cases of nosocomial infection with an infection rate of 9.62%. The sites of infection were oral mucosa, neck skin, respiratory tract, middle ear and urinary tract, and other parts, which accounted for 55.566.30 and 10.19 respectively. The positive rate was 89.81%. 106 strains of pathogenic bacteria were detected, including 64 strains of fungi, 29 strains of gram-negative bacteria and 13 strains of gram-positive bacteria. Among them, fungi were mainly Candida albicans (39.62%), gram-negative bacteria were Pseudomonas aeruginosa and Acinetobacter baumannii. Klebsiella pneumoniae, Escherichia coli, accounted for 10.38% 6.60,4.72% and 3.77% respectively. Gram-positive bacteria were mainly Staphylococcus aureus, Staphylococcus haemolyticus and Staphylococcus epidermidis, accounting for 4.72% 2.833% and 2.83% respectively. The patients with TNM stage 鈪，
本文编号：2158436
[Abstract]:Objective to investigate the characteristics of nosocomial infection pathogenic bacteria in nasopharyngeal carcinoma (NPC) patients and the risk factors of nosocomial infection in order to provide reference for the prevention and treatment of nasopharyngeal carcinoma nosocomial infection. Methods the clinical data of 1 123 inpatients with nasopharyngeal carcinoma from August 2001 to December 2012 were analyzed retrospectively. The data were statistically analyzed by SPSS17.0 software. The characteristics of pathogenic bacteria infection and related risk factors were analyzed. Results there were 108 cases of nosocomial infection with an infection rate of 9.62%. The sites of infection were oral mucosa, neck skin, respiratory tract, middle ear and urinary tract, and other parts, which accounted for 55.566.30 and 10.19 respectively. The positive rate was 89.81%. 106 strains of pathogenic bacteria were detected, including 64 strains of fungi, 29 strains of gram-negative bacteria and 13 strains of gram-positive bacteria. Among them, fungi were mainly Candida albicans (39.62%), gram-negative bacteria were Pseudomonas aeruginosa and Acinetobacter baumannii. Klebsiella pneumoniae, Escherichia coli, accounted for 10.38% 6.60,4.72% and 3.77% respectively. Gram-positive bacteria were mainly Staphylococcus aureus, Staphylococcus haemolyticus and Staphylococcus epidermidis, accounting for 4.72% 2.833% and 2.83% respectively. The patients with TNM stage 鈪，
本文编号：2158436
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