2013-2015年常州市武进区禽流感职业暴露人群及环境监测分析

发布时间：2018-08-28 11:59

【摘要】：目的分析禽流感病毒的变异情况及在职业暴露人群中感染状况的变化,发现感染来源,确定感染高危因素,监测禽流感病毒致病力和传播能力的改变,提供预警流感大流行依据。方法采集职业暴露人群血清标本用红细胞凝集抑制试验检测H5N1、H7N9抗体;采集环境标本用荧光定量PCR法检测禽流感病毒A型H5、H7、H9亚型核酸。结果采集职业暴露人群血清标本280份,H5N1、H7N9抗体均为阴性。家禽规模养殖场采集环境标本186份,阳性18份,阳性率9.7%;活禽交易市场采集环境标本98份,阳性15份,阳性率15.3%。结论常州市武进区禽流感职业高危人群尚未发现感染H5N1、H7N9病毒;家禽规模养殖场、活禽交易市场环境普遍存在禽流感病毒的污染,H5、H7和H9亚型是主要的病原体。
[Abstract]:Objective to analyze the variation of avian influenza virus and the changes of infection status in occupational exposed population, to find out the source of infection, to determine the high risk factors of infection, and to monitor the change of virulence and transmission ability of avian influenza virus. To provide a basis for early warning of an influenza pandemic. Methods Serum samples of occupational exposed population were collected for detection of H7N9 antibody by erythrocyte agglutination inhibition test, and the nucleic acid of Avian Influenza virus type A H5, H7, H9 subtype were detected by fluorescence quantitative PCR method in environmental samples. Results all 280 serum samples of occupational exposed population were negative for H 5N 1 H 7 N 9 antibody. 186 samples were collected from poultry farms, 18 samples were positive, the positive rate was 9.7%, 98 samples were collected from live poultry market, 15 samples were positive, the positive rate was 15.3B. Conclusion the occupational high risk population of avian influenza in Wujin District of Changzhou City has not been found to be infected with H5N1 1 and H7N9 virus, and the main pathogens are H5 H7 and H9 subtypes of avian influenza virus in poultry farms and live poultry markets.
【作者单位】：常州市武进区疾病预防控制中心;常州市疾病预防控制中心;
【分类号】：R511.7;R181.8

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