上海外来青壮年建筑工人慢性肾脏病流行病学研究

发布时间：2018-09-09 18:48

【摘要】：目的探讨上海外来青壮年建筑工人慢性肾脏病(CKD)患病率和危险因素,提高农民工群体CKD的早期诊断率和知晓率,并为制定农民工慢性疾病防治方案提供科学依据。方法采用整群随机抽样法对上海建工集团3 195名18~50岁外来建筑工人进行问卷调查,并检测肾脏损伤指标和相关危险因素,包括体格检查、尿常规+尿沉渣光学显微镜下检查、尿白蛋白/血清肌酐比值(ACR)、肾功能、血尿酸、血糖、血胆固醇、血红蛋白和肾脏B超检查等。采用肾脏病饮食改良(MDRD)简化公式计算估算的肾小球率过滤(eGFR)。3个月后对ACR检查异常者进行复查。结果在3 112名资料完整的外来建筑工人中,白蛋白尿患病率为9.9%,镜下血尿为3.0%,肾功能下降仅3例。该人群中CKD患病率为12.9%,知晓率为7.0%。高血压的患病率和知晓率分别为24.3%和13.6%。Logistic多因素因归分析结果提示,CKD危险因素依次为女性、收缩压升高、肾结石和糖代谢异常,而与年龄、吸烟、舒张压升高、血红蛋白、饮酒、血尿酸、血胆固醇和乙型肝炎表面抗原不相关。结论上海外来青壮年建筑工人的CKD患病率为12.9%,大部分处于CKD 1至2期,相关危险因素为女性、收缩压升高、肾结石和糖代谢异常。该人群对CKD和高血压的知晓率远低于全国平均水平。
[Abstract]:Objective to investigate the prevalence and risk factors of chronic kidney disease (CKD) among migrant workers in Shanghai, to improve the early diagnosis rate and awareness rate of CKD among migrant workers, and to provide scientific basis for the prevention and treatment of chronic disease among migrant workers. Methods A total of 3 195 foreign construction workers aged from 18 to 50 years old in Shanghai Construction Engineering Group were investigated by cluster random sampling, and renal injury indexes and related risk factors, including physical examination, routine urine sediment optical microscope examination, were examined. Urinary albumin / serum creatinine ratio (ACR),) renal function, serum uric acid, blood glucose, blood cholesterol, hemoglobin and kidney B ultrasonic examination. Glomerular rate filter (eGFR). Calculated by modified (MDRD) formula for kidney disease diet was re-examined in patients with abnormal ACR examination after 3 months. Results among 3 112 foreign construction workers with complete data, the prevalence rate of albuminuria was 9.9, hematuria under microscope was 3.0, and renal function was decreased in only 3 cases. The prevalence of CKD in this population was 12.9 and the awareness rate was 7.0. The prevalence rate and awareness rate of hypertension were 24.3% and 24.3%, respectively. The results of multivariate analysis indicated that the risk factors of CKD were female, systolic blood pressure increased, kidney stone and glucose metabolism abnormal, and age, smoking, increased diastolic blood pressure, hemoglobin, alcohol consumption. There was no correlation between serum uric acid, cholesterol and hepatitis B surface antigen. Conclusion the prevalence of CKD in the young and middle-aged construction workers of Shanghai is 12.9, most of them are in CKD stage 1 to 2. The related risk factors are high systolic blood pressure (SBP), abnormal renal calculi and glycometabolism. The population's awareness of CKD and hypertension was well below the national average.
【作者单位】：上海建工医院肾内科;
【基金】：上海市卫生局科研基金资助项目(20114288)
【分类号】：R181.3;R692

【共引文献】