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郑州市男男性接触人群艾滋病流行趋势及影响因素分析

发布时间:2018-10-29 11:30
【摘要】: 目的:了解郑州市男男性接触人群(MSM)的艾滋病流行状况和影响因素,分析MSM人群艾滋病流行趋势,为艾滋病疫情估计和预测提供相关信息,为制定艾滋病防治策略和干预措施提供科学依据。 方法:2005~2008年每年对郑州市的MSM人群进行匿名问卷调查,采用分层抽样方法,根据MSM来源的场所不同而分为两个层次:①公厕、公园等;②酒吧、夜总会、茶吧、浴池、桑拿等娱乐场所。再根据两个层次MSM人群的估计数,按比例抽样。调查内容包括:一般人口学信息、血清学信息、行为学信息和艾滋病知识有关信息等。用无菌注射器采集5ml静脉血,分离血清,进行HIV抗体、梅毒和丙型肝炎抗体检测。用EpiData3.1软件录入资料,用SPSS15.0软件进行统计分析,计数资料采用率进行描述分析,不同类别人群各种率的比较采用χ~2检验。 结果:①一般情况:2005~2008年共调查871人,未婚者578人,占66.36%;已婚者251人,占28.82%,其他占4.82%。4年年龄变化,经检验,F=64.38,P<0.05,有统计学意义,有低龄化趋势。共检测出HIV抗体阳性者38人,总阳性率为4.36%,共检测出梅毒阳性者56人,总阳性率为6.43%。871人中有664人在六个月内有两个或以上的同性性伴,占76.23%,有720人在六个月内有肛交性行为,占82.66%,其中246人每次均使用安全套,占34.17%。315人在六个月内有异性性伴,占36.17%,其中有68人有两个或两个以上的异性性伴。在最近六个月内付出金钱或为得到金钱而与他人发生过性行为者有80人,占9.18%。②流行趋势:2005~2008年MSM人群每年的HIV感染率分别为2.63%、3.36%、3.74%、5.49%,经χ~2检验,χ~2=3.147,P>0.05,无统计学意义,HIV感染率变化不显著;共检测出梅毒阳性56人,总的阳性率为6.43%。4年梅毒感染率比较,经χ~2检验,χ~2=19.127,P<0.05,有统计学意义,梅毒感染率有明显的上升趋势。③影响因素分析:多同性性伴组HIV阳性率明显高于单一同性性伴组(χ~2=5.524,P<0.05);不坚持使用安全套组HIV感染率明显高于全程坚持使用安全套组(χ~2=6.008,P<0.05);梅毒阳性组中HIV感染率明显高于梅毒阴性组(χ~2=26.941,P<0.05)。 结论:郑州市MSM人群中HIV感染率已经达到较高水平。安全套使用率低、多性伴、梅毒感染率增高等是促使HIV在该人群中快速传播的危险因素。
[Abstract]:Objective: to understand the prevalence and influencing factors of (MSM) among men who have sex with men in Zhengzhou, analyze the trend of AIDS epidemic in MSM population, and provide relevant information for the estimation and prediction of HIV / AIDS epidemic situation. To provide scientific basis for the formulation of AIDS prevention and treatment strategy and intervention measures. Methods: an anonymous questionnaire survey was conducted on MSM population in Zhengzhou from 2005 to 2008. The stratified sampling method was used. According to the location of MSM, it was divided into two levels: (1) Public toilets, parks and so on; Bar, nightclub, tea bar, bath, sauna and other entertainment places. Then according to the two levels of MSM population estimates, according to the proportion of sampling. The survey includes: general demographic information, serological information, behavioral information and AIDS related information. The venous blood of 5ml was collected with sterile syringe, and the serum was isolated and tested for HIV antibody, syphilis and hepatitis C antibody. EpiData3.1 software was used to input data, SPSS15.0 software was used to carry out statistical analysis, and counting data was used to describe the data. The 蠂 ~ 2 test was used to compare the various rates of different groups of people. Results: 1 General situation: a total of 871 people were investigated from 2005 to 2008, of which 578 were unmarried, accounting for 66.36; There were 251 married persons (28.82%) and the others in 4.82 years (P < 0.05). The results showed that there was a statistical significance and a trend of younger age. A total of 38 HIV antibody positive people were detected, and the total positive rate was 4.36. The total positive rate of syphilis was 56, and the total positive rate was 6.43.871. 664 of them had two or more same-sex partners within six months, accounting for 76.23%. There were 720 people who had anal sex within six months (82.66), 246 of whom used condoms every time, 34.17.315 had heterosexual partners within six months, 36.17. Sixty-eight of them had two or more heterosexual partners. There were 80 people who had sex with others in the last six months, accounting for 9.18.2 epidemic trend: the annual HIV infection rate of MSM population from 2005 to 2008 was 2.63% and 3.36% / 3.74%, respectively. 5.49, 蠂 ~ 2 test showed that there was no significant change in HIV infection rate. A total of 56 syphilis positive cases were detected. The total positive rate of syphilis was 6.43.4 years. 蠂 ~ 2 test showed that there was significant difference between the two groups (P < 0.05). The infection rate of syphilis increased significantly. 3 the positive rate of HIV in multiple sex partners was significantly higher than that in single sex partners (蠂 ~ 2 = 5.524, P < 0. 05). The infection rate of HIV in the group without condom use was significantly higher than that in the group of adherence to condom use (蠂 ~ 26.008, P < 0. 05), and the infection rate of HIV in the positive group of syphilis was significantly higher than that in the group of negative syphilis (蠂 ~ 2, 26.941, P < 0. 05). Conclusion: the infection rate of HIV in MSM population in Zhengzhou has reached a high level. Low condom use, multiple partners, and increased syphilis infection rate are the risk factors for rapid transmission of HIV in this population.
【学位授予单位】:郑州大学
【学位级别】:硕士
【学位授予年份】:2009
【分类号】:R512.91;R181.3

【引证文献】

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