双链季铵盐消毒剂对医院物体表面消毒效果研究

发布时间：2018-11-01 18:55

【摘要】：目的比较双链季铵盐消毒剂与含氯消毒剂对物体表面的消毒效果,为临床寻找一种安全环保、经济适用的消毒剂提供循证依据。方法 2014年7月分别采用3 000mg/L一次性双链季铵盐消毒湿巾和用500mg/L含氯消毒剂小毛巾消毒同一个物体表面的两个区域,采用平板压印法和细菌培养计数的方法,比较消毒前、消毒即刻及消毒后4h,两种消毒方法的合格率;用含有双链季铵盐消毒剂的一次性湿巾擦拭涂有多药耐药菌的病历夹物体表面,1min后采样,计算消毒前细菌数及消毒后灭菌率。结果含氯消毒液与一次性双链季铵盐消毒湿巾即刻消毒合格率分别为90.91%和94.55%,消毒液消毒4h后合格率分别为67.31%和78.43%,差异均无统计学意义;一次性双链季铵盐消毒湿巾对涂有多药耐药菌的物体表面消毒后灭菌率≥99.96%;在ICU,每天消毒成本一次性双链季铵盐消毒湿巾为141.44元,含氯消毒剂为174.14元。结论一次性双链季铵盐表面消毒湿巾性价比高,绿色环保、操作简便、消毒效果可靠,可在医疗机构推广使用。
[Abstract]:Objective to compare the efficacy of double chain quaternary ammonium salt disinfectant and chlorinated disinfectant in disinfection of object surface, and to provide evidence basis for clinical application of a safe, environmentally friendly, economical and applicable disinfectant. Methods in July, 2014, two areas of the same object were disinfected with 3 000mg/L one-off double chain quaternary ammonium salt and 500mg/L chlorine disinfectant respectively. The method of plate imprint and bacterial culture counting were used. The eligible rates of the two disinfection methods were compared before, immediately and 4 hours after disinfection. A disposable wet towel containing double chain quaternary ammonium salt disinfectant was used to wipe the surface of the medical record clip coated with multidrug resistant bacteria. After sampling after 1min, the number of bacteria before disinfection and the sterilization rate after disinfection were calculated. Results the eligible rates of immediate disinfection of chlorinated disinfectant solution and one-off double chain quaternary ammonium salt disinfection wet towel were 90.91% and 94.555.After disinfection, the qualified rates were 67.31% and 78.43%, respectively. There was no significant difference between them. The sterilization rate of disposable double chain quaternary ammonium salt disinfection wipes on the surfaces of objects coated with multidrug resistant bacteria was greater than 99.96.The cost of disinfection of disposable double chain quaternary ammonium salts in ICU, was 141.44 yuan per day, and that of chlorine disinfectants was 174.14 yuan. Conclusion the disposable double chain quaternary ammonium salt surface disinfection wet towel has the advantages of high cost performance, green environmental protection, simple operation, reliable disinfection effect and can be popularized and used in medical institutions.
【作者单位】：安庆市第一人民医院感染管理科;安徽医科大学第一附属医院感染管理科;
【基金】：安徽省卫生厅预防医学与公共卫生科研基金资助项目(2011Y0224)
【分类号】：R187.2

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