新型登革热传播媒介监测诱蚊诱卵器开发应用研究
发布时间：2019-02-18 09:23
【摘要】：登革热是由蚊虫传播登革热病毒引起的急性传染病，随着城市化和全球一体化的快速发展、过分依赖杀虫剂导致抗药性等问题20世纪80年代以来流行越来越严重，全球每年有百多万病例，近25亿人口受到登革热的威胁。我国自1978年广东省再次爆发本病流行后，有不断蔓延并向北移动扩散的趋势。由于登革热仍没有特异性疫苗和治疗药物，所以加强登革热及媒介监测和控制仍是当前最有效的预防措施，WHO特别强调加强新型敏感的媒介监测方法的研究。本课题来源于广东省疾病预防控制中心的广东省应急病原检测重点实验室启动研究项目，属广东省重点科技项目(2003B60127)。 本研究目的是根据登革热必须通过蚊虫的叮咬传播和蚊虫吸血后产卵的特点，研究开发对伊蚊特异性高的诱蚊诱卵器(Mosquito and oviposition trap，Mosq-ovitrap)，建立科学高效、简便可行的监测方法，既监测社区环境伊蚊密度，又采集社区环境中吸血后最可能带毒的蚊虫，，利用PCR和细胞培养等技术对蚊虫进行登革热病毒的带毒监测，建立简易、科学、可行的登革热媒介的监测体系，再结合登革热疾病监测，为建立登革热可能流行的分级预警体系奠定基础。 1．诱蚊诱卵器(Mosq-ovitrap)的设计开发研究：根据白纹伊蚊喜欢趋向黑色、在阴凉潮湿的场所栖息活动，吸血后需寻找容器清水型积水，并在潮湿粗糙表面上产卵的生态特点，参考美国开发的诱卵杯，结合诱蝇笼的捕蝇原理，有针对性设计诱蚊诱卵器。
[Abstract]:Dengue is an acute infectious disease caused by mosquito-borne dengue virus. With the rapid development of urbanization and global integration, it has become more and more serious since the 1980s, and more than a million cases of the world each year, Nearly 2.5 billion people are threatened by dengue fever. Since the outbreak of this disease in Guangdong Province in 1978, China has a tendency to spread and spread to the north. Since dengue still has no specific vaccine and therapeutic drug, it is still the most effective preventive measure to strengthen the monitoring and control of dengue and medium, and the WHO has placed special emphasis on strengthening the research of new sensitive media monitoring methods. This project is based on Guangdong Provincial Center for Disease Control and Prevention, the key laboratory for emergency pathogen detection in Guangdong Province, and belongs to the key science and technology project of Guangdong Province (2003B60127). The purpose of this study is to develop a scientific and efficient and feasible monitoring method for the development of a scientific and efficient and feasible monitoring method, based on the fact that dengue has to be spread through the bite of the mosquito and the characteristics of the oviposition after the mosquito sucks blood. in that invention, the density of the mosquito in the community environment is monitored, the mosquito which is most likely to be infected after the blood is sucked in the community environment is collected, the virus of the dengue virus is monitored by the technology of PCR and cell culture and the like, and a simple, scientific and feasible monitoring system of the dengue medium is established, in combination with that surveillance of dengue disease, it may be possible to establish dengue fever The foundation of the classification and early warning system is laid. 1. The design and development of the Moq-ovitrap: according to the tendency of the Aedes albopictus to tend to be black, live in a cool and humid place. After the blood is sucked, it is necessary to find the clear water type of the container and to be rough in the damp and rough. The ecological characteristic of laying eggs on the surface, referring to the development of the egg-inducing cup and the knot in the United States.
【学位授予单位】：第一军医大学
【学位级别】：博士
【学位授予年份】：2006
【分类号】：R184
本文编号：2425715
[Abstract]:Dengue is an acute infectious disease caused by mosquito-borne dengue virus. With the rapid development of urbanization and global integration, it has become more and more serious since the 1980s, and more than a million cases of the world each year, Nearly 2.5 billion people are threatened by dengue fever. Since the outbreak of this disease in Guangdong Province in 1978, China has a tendency to spread and spread to the north. Since dengue still has no specific vaccine and therapeutic drug, it is still the most effective preventive measure to strengthen the monitoring and control of dengue and medium, and the WHO has placed special emphasis on strengthening the research of new sensitive media monitoring methods. This project is based on Guangdong Provincial Center for Disease Control and Prevention, the key laboratory for emergency pathogen detection in Guangdong Province, and belongs to the key science and technology project of Guangdong Province (2003B60127). The purpose of this study is to develop a scientific and efficient and feasible monitoring method for the development of a scientific and efficient and feasible monitoring method, based on the fact that dengue has to be spread through the bite of the mosquito and the characteristics of the oviposition after the mosquito sucks blood. in that invention, the density of the mosquito in the community environment is monitored, the mosquito which is most likely to be infected after the blood is sucked in the community environment is collected, the virus of the dengue virus is monitored by the technology of PCR and cell culture and the like, and a simple, scientific and feasible monitoring system of the dengue medium is established, in combination with that surveillance of dengue disease, it may be possible to establish dengue fever The foundation of the classification and early warning system is laid. 1. The design and development of the Moq-ovitrap: according to the tendency of the Aedes albopictus to tend to be black, live in a cool and humid place. After the blood is sucked, it is necessary to find the clear water type of the container and to be rough in the damp and rough. The ecological characteristic of laying eggs on the surface, referring to the development of the egg-inducing cup and the knot in the United States.
【学位授予单位】：第一军医大学
【学位级别】：博士
【学位授予年份】：2006
【分类号】：R184
【引证文献】
相关期刊论文 前1条
1 于德宪;任旭琦;周文;廖玉学;陈清;俞守义;;白纹伊蚊诱蚊诱卵器应用效果的现场研究[J];热带医学杂志;2008年04期
本文编号：2425715
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