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天津市东丽区肾病综合征出血热流行因素研究

发布时间:2019-03-30 12:58
【摘要】:目的 肾病综合征出血热是由几种啮齿动物携带的多种不同型汉坦病毒引起的伴有肾综合征的一类出血热的综合名称,是在世界上分布较广,发病较多,危害性较大的一种病毒性出血热,已成为全球性的公共卫生问题。现对1997~2005年天津市东丽区肾病综合征出血热流行因素进行研究,以制定科学的预防措施,减少动物疫源性疾病向人间的传播,避免新的传染病的发生,保证社会秩序的顺利发展。 方法 对东丽区1997~2005肾病综合征出血热流行状况进行统计描述和相关分析,对鼠带毒率、气象资料、农业资料、人口资料采用Excel进行资料整理,并将发病情况与流行因素采用SPSS11.5软件包进行统计分析。 结果 天津市东丽区肾病综合征出血热自1997年开始出现流行趋势,之后逐渐增多到2002年达到高峰,之后逐年下降。9年共发生肾病综合征出血热105例,死亡4例,累计发病率为2.90/10万,死亡率为0.11/10万,病死率3.81%;具有明显的季节差异,4~5月为发病高峰,占发病总数的44.76%;呈高度散发,全区11个乡镇街70个行政村都有病例发生;30岁组发病数最高,占总发病数的33.33%;男性多于女性,男女之比为3.57∶1;农民发病人数占总发病人数的26.67%,外地流动人口发病占发病总数的54.29%;经检验鼠带毒指数与疫情发病率基本趋势一致;平均气温与发病率呈正相关(r_s=0.746,P=0.021);降水量与发病率呈负相关(r_s=-0.695,P=0.038);粮食种植面积与发病率呈负相关趋势(r_s=-0.167,P=0.532)。 结论 东丽区属于原始宿主为褐家鼠的Ⅱ型汉城病毒引起的以家鼠型疫情为主的疫区。90年代中期以后流动人口的大量涌人;本地区优势鼠种的变迁;
[Abstract]:Objective hemorrhagic fever with nephrotic syndrome (HFRS) is a kind of hemorrhagic fever with renal syndrome caused by a variety of different types of Hantavirus carried by several rodents, and it is widely distributed in the world. A serious viral hemorrhagic fever has become a global public health problem. The epidemic factors of hemorrhagic fever with nephrotic syndrome (HFRS) in Dongli district of Tianjin in 1997 / 2005 were studied in order to formulate scientific preventive measures to reduce the spread of animal epidemic diseases to human and to avoid the occurrence of new infectious diseases. To ensure the smooth development of social order. Methods the epidemic situation of hemorrhagic fever with nephrotic syndrome (HFRS) in Dongli district in 1997-2005 was described statistically and analyzed. The rate of virus-carrying, meteorological data, agricultural data and population data in Dongli district were collected by Excel. The incidence and epidemic factors were analyzed by SPSS11.5 software package. Results the epidemic trend of hemorrhagic fever with nephrotic syndrome (HFRS) in Dongli district of Tianjin began in 1997, then increased gradually to the peak in 2002, and then decreased year by year. There were 105 cases of hemorrhagic fever with nephrotic syndrome (HFRS) and 4 cases of death in 9 years. The cumulative morbidity was 2.90 / one hundred thousand, the mortality was 0.11 / one hundred thousand and the mortality was 3.81%. There were obvious seasonal differences, the incidence peak was from April to May, accounting for 44.76% of the total number of cases, showing a high degree of distribution, 11 rural streets and 70 administrative villages in the whole region had cases occurring, the incidence of the 30-year-old group was the highest, accounting for 33.33% of the total number of cases, the number of cases in the 30-year-old group was the highest. Male was more than female, the ratio of male to female was 3.57%, the number of peasants was 26.67%, the floating population accounted for 54.29% of the total, the virus-carrying index of tested mice was consistent with the incidence rate of epidemic situation. There was a positive correlation between mean air temperature and incidence (r = 0.746, P = 0.021), and a negative correlation between precipitation and incidence (r = 0.695, P = 0.038). There was a negative correlation between grain planting area and incidence (r = 0.167, P = 0.532). Conclusion Dongli district belongs to the endemic area mainly caused by type 鈪,

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