贵港市急性脑炎及脑膜炎症候群病原体监测

发布时间：2019-06-07 20:17

【摘要】：目的了解华南地区急性脑炎及急性脑膜炎的发病强度、病原谱和流行病学特征,为急性脑炎、脑膜炎的临床诊治和预防控制提供参考依据。方法在广西贵港市建立涵盖市辖区、桂平市和平南县的急性脑炎、脑膜炎流行病学监测网络,按照筛检标准评估疑似病例,进行流行病学调查和采样,对标本开展细菌学培养和10种常见病毒检测。结果 2007年5月—2008年10月监测期内,共评估急性脑炎及急性脑膜炎症候群病例883例,死亡41例,细菌学培养和PCR检测发现存在肺炎链球菌、流脑、Hib、猪链球菌等致病菌,病毒学检测发现肠道病毒、腮腺炎病毒和乙脑病毒是病毒性脑炎脑膜炎的主要病原,贵港市确诊的细菌性、病毒性脑炎脑膜炎年均发病率分别为0.92/10万和6.42/10万,细菌性、病毒性脑炎脑膜炎均以夏秋季多见,10岁以下儿童为主,职业分布细菌性脑炎脑膜炎以散居儿童和农民为主,分别占48.65%和29.73%,病毒性脑炎脑膜炎以散居儿童和学生为主,分别占59.64%和21.08%。结论广西贵港市急性脑炎脑膜炎病例以病毒性感染占多数,病原诊断的细菌性脑炎脑膜炎发病率处于较低水平。
[Abstract]:Objective to investigate the incidence, etiological spectrum and epidemiological characteristics of acute meningitis and acute meningitis in South China, and to provide reference for clinical diagnosis, treatment, prevention and control of acute meningitis. Methods the epidemiological surveillance network of acute meningitis and meningitis covering municipal district, Guiping City and Pingnan County was established in Guigang City, Guangxi. The suspected cases were evaluated according to the screening criteria, and epidemiological investigation and sampling were carried out. Bacteriological culture and detection of 10 common viruses were carried out. Results during the monitoring period from May 2007 to October 2008, a total of 883 cases of acute meningitis and acute meningitis were evaluated, 41 cases died. Streptococcus pneumoniae, meningococci and Streptococcus suis Hib, were found by bacteriological culture and PCR detection. Virological detection showed that enterovirus, mumps virus and Japanese meningitis virus were the main pathogens of viral meningitis. The average annual incidence of viral meningitis diagnosed in Guigang city was 0.92 / 100000 and 6.42 / 100000, respectively. Bacterial and viral meningitis were more common in summer and autumn, mainly in children under 10 years old. The occupational distribution of bacterial meningitis was mainly in diasporic children and farmers, accounting for 48.65% and 29.73%, respectively. Viral meningitis was mainly in diasporic children and students, accounting for 59.64% and 21.08%, respectively. Conclusion viral infection is the most common case of acute meningitis in Guigang City, Guangxi, and the incidence of bacterial meningitis diagnosed by pathogen is at a low level.
【作者单位】：广西壮族自治区疾病预防控制中心;中国疾病预防控制中心;世界卫生组织;
【基金】：卫生部和世界卫生组织流行性脑脊髓膜炎和流行性乙型脑炎等疾病监测合作项目(AMES Project) 广西壮族自治区卫生厅计划课题(Z2008204) 广西青年基金(2011GXNSFB018090)
【分类号】：R181.3

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