铜川市流行性乙型脑炎发病特征分析
发布时间：2019-08-09 11:29
【摘要】：目的了解铜川市乙脑发病特征及人群抗体水平,为有效防控乙脑提供科学依据。方法采用描述流行病学方法,对铜川市乙脑病例进行统计分析,并在铜川市宜君县随机抽取健康人群采集静脉血检测乙脑中和抗体。结果铜川市1960-2012年共报告乙脑病例649例,死亡59例,年均发病率为2.07/10万,死亡率为0.19/10万,病死率为9.09%。发病呈明显的季节特点,近年来职业分布上以农民、民工为多,15岁以上人群病例占总病例数的93.10%,年龄别发病率以60岁以上人群最高;共采集健康人群血样216对,乙脑流行季节前,健康人群中和抗体阳性率24.07%,抗体几何平均滴度(GMT)1∶3.04;流行季节后,健康人群乙脑中和抗体阳性率为26.39%,抗体几何平均滴度(GMT)1∶3.29,流行季节前后中和抗体阳性率和抗体几何平均滴度差异均无统计学意义。结论乙脑疫苗接种是铜川市预防乙脑最有效的途径,铜川市健康人群乙脑抗体水平主要受疫苗接种影响。在做好适龄儿童免疫接种的同时,对成人也应开展乙脑疫苗强化免疫,建立整个人群的免疫屏障。
[Abstract]:Objective to investigate the characteristics of Japanese B and the level of antibody in Tongchuan city, and to provide scientific basis for the effective prevention and control of Japanese B. Methods the cases of Japanese B in Tongchuan City were statistically analyzed by descriptive epidemiological method, and venous blood samples were collected from healthy people in Yijun County of Tongchuan City to detect the neutralizing antibody of Japanese B. Results A total of 649 cases of Japanese B were reported in Tongchuan City in 2012. 59 cases died. The average annual incidence was 2.07 / 100000, the mortality rate was 0.19 / 100000, and the fatality rate was 9.09%. In recent years, farmers and migrant workers accounted for 93.10% of the total cases, and the age-specific incidence was the highest in the population over 60 years old. A total of 216 pairs of blood samples were collected from healthy people. Before the epidemic season, the positive rate of neutralizing antibody was 24.07% and the geometric mean titer of antibody (GMT) was 1 鈮，
本文编号：2524762
[Abstract]:Objective to investigate the characteristics of Japanese B and the level of antibody in Tongchuan city, and to provide scientific basis for the effective prevention and control of Japanese B. Methods the cases of Japanese B in Tongchuan City were statistically analyzed by descriptive epidemiological method, and venous blood samples were collected from healthy people in Yijun County of Tongchuan City to detect the neutralizing antibody of Japanese B. Results A total of 649 cases of Japanese B were reported in Tongchuan City in 2012. 59 cases died. The average annual incidence was 2.07 / 100000, the mortality rate was 0.19 / 100000, and the fatality rate was 9.09%. In recent years, farmers and migrant workers accounted for 93.10% of the total cases, and the age-specific incidence was the highest in the population over 60 years old. A total of 216 pairs of blood samples were collected from healthy people. Before the epidemic season, the positive rate of neutralizing antibody was 24.07% and the geometric mean titer of antibody (GMT) was 1 鈮，
本文编号：2524762
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