小儿七氟烷麻醉中不同剂量瑞芬太尼持续输注下自主呼吸情况比较

发布时间：2018-01-05 15:02

  本文关键词：小儿七氟烷麻醉中不同剂量瑞芬太尼持续输注下自主呼吸情况比较　出处：《世界最新医学信息文摘》2016年94期 　论文类型：期刊论文

  更多相关文章： 小儿七氟烷麻醉 瑞芬太尼 持续输注 自主呼吸

【摘要】：目的对比分析小儿七氟烷麻醉中不同剂量瑞芬太尼持续输注下自主呼吸情况。方法选择从2012年12月至2014年12月在本院进行斜视矫正手术治疗的患儿120例,以30例为1组,分为甲、乙、丙、丁四组,甲、乙、丙三组持续输注瑞芬太尼,剂量分别是0.03μg/kg/min、0.06μg/kg/min、0.09μg/kg/min。丁组持续输注0.9%生理盐水。观察并对比两组的应用效果。结果组间比较:甲、乙、丁三组在B时RR达到最低,随后逐渐上升,在E时有所下降;丙组RR随时间推移逐渐降低,在E时有所升高,比较差异均具有统计学意义(P0.05)。组间比较,四组A时、B时的RR无显著差异(P0.05):与丁组相比,甲乙丙三组CDE的RR更低(P0.05),且丙组低于甲组和乙组(P0.05),甲组和乙组无显著差异(P0.05)。组内比较,甲、乙、丁的VT先逐渐降低,D时升高,E时降低,比较差异均具有统计学意义(P0.05);丙组各时点VT无显著差异(P0.05);组间比较,四组各时点的VT无无显著差异(P0.05)。结论在小儿七氟烷麻醉中以0.03-0.09μg/kg/min速率持续输注瑞芬太尼可抑制患儿的自主呼吸,其中0.03--0.06μg/kg/min输注速率可在满足镇痛需要的基础上尽可能保留患儿的自主呼吸,应根据手术需要进行调整。
[Abstract]:Objective to compare and analyze the spontaneous respiration during sevoflurane anesthesia in children with different doses of remifentanil continuous infusion. Methods from December 2012 to December 2014, we performed strabismus correction surgery in our hospital. 120 cases were children. 30 cases were divided into three groups: group A, B, C, D, A, B, C, D, A, B, C and C were continuously infused with remifentanil at a dose of 0.03 渭 g / kg / kg / min, 0.06 渭 g / kg / min, respectively. 0.09 渭 g / kg 路min 路min group was continuously infused with 0.9% normal saline. The results showed that the RR of group A, B and D was the lowest in B time. Then it increased gradually and decreased at E; The RR of group C decreased gradually with time and increased at E, the difference was statistically significant (P 0.05). There was no significant difference in RR between group B and group D (P 0.05): compared with group D, the RR of CDE in group A, B and C was lower than that in group A and group B, and the RR of group C was lower than that of group A and group B (P 0.05). There was no significant difference between group A and group B (P 0.05). VT of group A, B and D decreased gradually at the time of increasing E, and the difference was statistically significant (P 0.05). There was no significant difference in VT between group C and group C (P 0.05). Group comparison. There was no significant difference in VT between the four groups at different time points (P0.05). Conclusion continuous infusion of remifentanil at a rate of 0.03-0.09 渭 g / kg / min during sevoflurane anesthesia in children can inhibit the spontaneous respiration of children. The infusion rate of 0.03-0.06 渭 g / kg / min can keep the patient's spontaneous respiration on the basis of satisfying the need of analgesia, and should be adjusted according to the need of operation.
【作者单位】： 江苏省盐城市阜宁县人民医院麻醉科;
【分类号】：R726.1
【正文快照】： 0引言不蓄积、起效快、镇痛效果显著是瑞芬太尼的优势所在,广泛应用于小儿浅表短小手术的七氟烷麻醉中[1]。相关的研究指出,七氟烷复合瑞芬太尼可严重抑制成人患者的自主呼吸,其对小儿患者的影响还不明朗。为了验证小儿七氟烷麻醉中持续输注瑞芬太尼对自主呼吸的影响,本文特以，

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