我院特殊诊疗操作中预防性使用抗菌药物调查分析

发布时间：2018-01-17 13:41

本文关键词：我院特殊诊疗操作中预防性使用抗菌药物调查分析　出处：《中国药房》2017年26期 　论文类型：期刊论文

【摘要】：目的:调查我院特殊诊疗操作中预防性使用抗菌药物的情况,为抗菌药物合理使用提供参考。方法:收集我院2016年1-8月进行特殊诊疗操作的患者,对其预防性使用抗菌药物的情况进行统计、分析。结果:纳入调查的149例患者中,有62例预防性使用了抗菌药物,使用率为41.61%。62例使用抗菌药物的患者中,有5例为口服,其余均为注射给药。共使用抗菌药物九大类18个品种,合计69例次,其中头孢菌素类使用频次为49例次(71.01%),头孢菌素类使用频次最高的3个品种依次为头孢地嗪、头孢替安和头孢唑林。其中,血管(包括冠状动脉)造影术、支架植入术均未预防性使用抗菌药物;其他诊疗操作的抗菌药物预防性使用率均超过50%;输尿管镜和膀胱镜检查、震波碎石术的预防性使用抗菌药物情况较复杂,且选药品种起点较高。单一用药59例(95.16%);二联用药3例(4.84%)。用药时机为术前0.5~2 h或麻醉开始时有41例(66.13%)。用药持续时间≤24 h的有18例(29.03%);24~48 h的有11例(17.74%)。结论:我院血管(包括冠状动脉)造影术、支架植入术和腹膜透析管植入术符合预防性使用抗菌药物规范;其他特殊诊疗操作存在给药指征把握不严、药物选择起点过高和给药时机不适宜及疗程偏长等问题。
[Abstract]:Objective: to investigate the situation of prophylactic use of antimicrobial agents in special diagnosis and treatment in our hospital, and to provide reference for rational use of antimicrobial agents. Methods: to collect the patients undergoing special diagnosis and treatment in our hospital from 2016 to August. Statistics and analysis of prophylactic use of antimicrobial agents. Results: 62 of 149 patients included in the study had prophylactic use of antimicrobial agents. The usage rate was 41.61%. Of the 62 patients who used antibiotics, 5 cases were taken orally and the rest were administered by injection. A total of 18 kinds of antimicrobial agents were used in nine categories, 69 times in total. The frequency of use of cephalosporins was 71.01 in 49 cases, and the three varieties with the highest frequency of use of cephalosporins were cefodizine, ceftidine and cefazolin. Angiography (including coronary artery), stent implantation did not prevent the use of antimicrobial agents; The prophylactic use rate of antimicrobial agents in other diagnosis and treatment operations was more than 50. Ureteroscopy and cystoscopy showed that prophylactic use of antimicrobial agents in shock wave lithotripsy was more complicated and the starting point of drug selection was higher. The timing of the drug was 0.52h before operation or 66.13g at the beginning of anaesthesia. The duration of the drug was less than 24 h in 18 cases (P < 0.05). 29.03; Conclusion: angiography, stent implantation and peritoneal dialysis tube implantation in our hospital are in accordance with the prophylactic use of antimicrobial drugs. In other special diagnosis and treatment operations, the indications of drug administration are not strict, the starting point of drug selection is too high, the timing of administration is not appropriate and the course of treatment is too long.
【作者单位】：嵊州市人民医院药剂科;
【分类号】：R95
【正文快照】： 近年来,国家卫生计生委加强了抗菌药物临床应用的管理,在抗菌药物临床应用管理原则中,围术期预防性使用抗菌药物的用药指征、给药时机、药物选择、用药疗程、联合用药等在政策层面的规定相对明确详尽,管理依据充分,其应用相对较易引向标准化、规范化[1]。我院自2012年开始对Ⅰ

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