静-吸复合全麻对肝癌术中麻醉效果及患者肝功能的影响

发布时间：2018-03-14 13:34

本文选题：静-吸复合全麻　切入点：硬膜外联合静脉麻醉　出处：《实用癌症杂志》2016年05期 　论文类型：期刊论文

【摘要】：目的观察静-吸复合全麻与硬膜外联合静脉麻醉对肝癌手术中麻醉效果以及肝功能的影响。方法临床纳入行肝叶切除术的肝癌患者70例,根据麻醉方式的不同分为研究组与对照组。研究组进行静-吸复合全麻,对照组进行硬膜外联合静脉麻醉。观察两组患术中情况(包括用药情况、术中出血量、术中输液量等)、术后情况(包括自主呼吸恢复时间、睁眼时间、拔管时间以及清醒时间)、肝功能情况等。结果研究组芬太尼、乌拉地尔、维库溴铵等使用剂量分别为(0.18±0.02)mg、(24.85±12.37)mg、(19.81±6.11)mg,对照组分别为(0.47±0.06)mg、(57.53±12.01)mg、(15.72±11.92)mg,差异均有显著性(P均0.05);研究组自主呼吸恢复时间、睁眼时间、拔管时间、清醒时间分别为(424.85±81.37)s、(513.81±72.11)s、(634.59±141.15)s、(2.81±1.70)min,对照组分别为(577.23±152.01)s、(571.36±97.36)s、(757.46±132.25)s、(4.91±1.53)min,差异均有显著性(P均0.05);研究组谷丙转氨酶(ALT)、谷草转氨酶(AST)水平分别为(112.85±61.40)U/L、(130.81±72.11)U/L,对照组分别为(243.23±152.01)U/L、(241.82±121.92)U/L,差异均无显著性(P均0.05)。结论静-吸复合全麻对肝癌手术中患者的肝功能影响较小,且能够减少麻醉药物的应用,患者苏醒时间快,值得推广。
[Abstract]:Objective To observe the effect of static inhalation anesthesia combined with epidural anesthesia and intravenous anesthesia on influence effect of liver function in liver cancer surgery. In 70 patients with hepatocellular carcinoma underwent hepatectomy with clinical method, according to the different methods of anesthesia were divided into study group and control group. The study group were static suction compound anesthesia, control group for epidural anesthesia combined with intravenous anesthesia. Observe two groups of intraoperative (including medication, blood loss, intraoperative transfusion volume), surgery (including the recovery time of spontaneous breathing, eye opening time, extubation time and recovery time), liver function and so on. The results of study group fentanyl, urapidil use, vecuronium dose was (0.18 + 0.02) Mg, (24.85 + 12.37) Mg, (19.81 + 6.11) Mg, the control group were (0.47 + 0.06) Mg, (57.53 + 12.01) Mg, (15.72 + 11.92) Mg, there were significant differences (P < 0.05); research group of spontaneous breathing recovery Between the time of eye opening, extubation time, waking time was (424.85 + 81.37) s, (513.81 + 72.11) s, (634.59 + 141.15) s, (2.81 + 1.70) min, the control group were (577.23 + 152.01) s, (571.36 + 97.36) s, (757.46 + 132.25) s, (4.91 + 1.53) min, there were significant differences (P < 0.05); the study group of alanine aminotransferase (ALT), aspartate aminotransferase (AST) levels were (112.85 + 61.40) U/L, (130.81 + 72.11) U/L, the control group were (243.23 + 152.01) U/L, (241.82. 121.92) U/L, the difference was not significant (P < 0.05). Conclusion the static absorption has little effect on liver function of patients with hepatocellular carcinoma combined with general anesthesia in operation, and can reduce the application of narcotic drugs, patients with fast recovery time, worthy of promotion.

【作者单位】：内蒙古医科大学附属医院;
【分类号】：R614;R735.7

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