不同初始剂量丙泊酚在无痛胃镜麻醉中的效果探讨

发布时间：2018-03-17 12:14

本文选题：丙泊酚　切入点：无痛胃镜　出处：《中国现代医生》2016年31期 　论文类型：期刊论文

【摘要】：目的探讨不同初始剂量丙泊酚麻醉在无痛胃镜检查中的有效性,安全性和高效性。方法选择100例胃镜检查患者,ASA I~Ⅲ级,年龄20~80岁,体重50~70 kg,无失代偿心肺疾病,肝肾功能无明显障碍,按照自愿原则分为A、B两组各50例:A组为小初始剂量丙泊酚(1.5~2.0)mg/kg+局麻药组,B组为较大初始剂量丙泊酚组(2.1~3.0)mg/kg,监测所有患者检查前、中、后的SBP、DBP、HR、Sp O2变化,咽喉反射,体动,睁眼时间,起身站立时间,胃镜操作时间,检查成功率及愿意接受复查率等。结果 A、B两组患者的SBP、DBP、HR和Sp O2没有明显差异,其中A组没有需要抬下颌的患者,B组需要抬下颌的患者有11例,两组均没有呼吸暂停;A、B两组咽喉反射、体动、胃镜操作时间、检查成功率及愿意复诊率差异无统计学意义(P0.05);与B组比较,A组睁眼和起身站立时间均缩短(P0.05)。结论小初始剂量丙泊酚麻醉配合局麻药与单纯较大剂量丙泊酚麻醉在胃镜检查方面有同样完善的抑制咽喉反射和体动的效果,而且前者比后者对呼吸系统的影响更小、更安全,睁眼时间及起身站立时间均明显缩短,说明小初始剂量丙泊酚麻醉在门诊短小手术中更有优势,效率更高。
[Abstract]:Objective to investigate the efficacy, safety and efficiency of different initial doses of propofol anesthesia in painless gastroscopy. Methods 100 patients with ASA I ~ III grade, aged 2080 years, weighing 50 ~ 70 kg, had no decompensated cardiopulmonary disease. According to the voluntary principle, the liver and kidney were divided into two groups: group A (n = 50) and group A (n = 50): small initial dose of propofol (1.5 mg / kg) and 2.0 mg / kg propofol (group B). The changes of SBPDBPHRP / Sp O _ 2 were monitored before, during and after the examination in group B with a larger initial dose of propofol (2.1g / kg) and 3.0 mg / kg of propofol (group B). Pharynx reflex, body movement, eye opening time, standing up time, gastroscopy operation time, successful rate of examination and willingness to be reexamined were not significantly different between the two groups. There were 11 patients in group B with no need of mandibular lifting. There were no apnea, no apnea, no laryngeal reflex, body movement, and gastroscopy in both groups. Compared with group B, the time of opening eyes and standing up was shortened in group A. conclusion small initial dose of propofol anesthesia combined with local anesthetic and simple large dose of propofol were used in the treatment of propofol. Gastroscopy has the same perfect effect of inhibiting pharynx reflex and body movement. Compared with the latter, the former has less and safer influence on respiratory system, and the time of opening eyes and standing up is obviously shortened, which indicates that small initial dose of propofol anesthesia has more advantages and higher efficiency in short outpatient surgery.
【作者单位】：大连市友谊医院麻醉科;
【分类号】：R614

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