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我国老年患者术后谵妄危险因素的系统评价

发布时间:2018-03-18 10:46

  本文选题:老年人 切入点:谵妄 出处:《中国全科医学》2015年10期  论文类型:期刊论文


【摘要】:目的探讨我国老年患者术后谵妄的危险因素,为临床制定干预措施提供依据。方法检索万方数据资源系统、相关期刊论文(CNKI)、维普信息资源系统(VIP),收集建库至2013年12月公开发表的关于老年患者术后谵妄危险因素研究文献,按纳入和剔除标准进行筛选,采用Rev Man 5.2软件对病例对照文献进行Meta分析,对病例总结文献统计各危险因素的发生率。结果共纳入16篇文献,其中病例对照8篇,病例总结8篇。病例对照文献累计病例353例、对照2 008例。老年术后谵妄各因素合并OR值(95%CI)分别为:低氧血症2.58(1.59,4.18)、合并肺部感染4.76(1.36,16.67)、合并高血压2.16(1.20,3.89)、合并冠心病1.50(0.82,2.73)、术后疼痛3.18(1.63,6.20)、全身麻醉3.64(0.94,14.11)、手术时间32.30(-37.67,102.27)、高龄(≥70岁)0.99(-0.46,2.45)。Meta分析结果显示,低氧血症、合并肺部感染、合并高血压、术后疼痛是老年患者术后谵妄的危险因素(P0.05)。病例总结文献累计病例共404例,其中低氧血症、合并高血压的发生率较高,分别为62.6%(253例)、55.9%(226例)。结论术前合并高血压、肺部感染,术后低氧血症、疼痛是老年患者术后谵妄的危险因素。
[Abstract]:Objective to explore the risk factors of postoperative delirium in elderly patients in China, and to provide evidence for clinical intervention. The full text database of Chinese periodicals, CNKI, Weip Information Resource system (Wip), collected and published literatures on risk factors of postoperative delirium in elderly patients until December 2013, and screened them according to the criteria of inclusion and exclusion. Rev Man 5.2 software was used for Meta analysis of case-control literature, and the incidence of risk factors in the literature was analyzed. Results 16 articles were included, 8 of which were case-control. Eight cases were summarized. The total number of cases in the case-control literature was 353. In the control group of 2 008 cases, the factors of postoperative delirium in elderly patients with OR value of 95 CI were as follows: hypoxemia 2.581.59 / 4.18, pulmonary infection 4.761.3616.67, hypertension 2.16 / 1.20 / 3.89, coronary heart disease 1.50 / 0.822.73a, postoperative pain 3.181.63 / 6.20, general anesthesia 3.644.0.94 / 14.11a, operation time 32.30-637.7/ 102.27. the results of Meta analysis showed that the aged (鈮,

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