胃癌合并糖尿病病人围麻醉期血清胰岛素、皮质醇和血糖变化

发布时间：2018-03-23 23:14

本文选题：糖尿病　切入点：皮质醇　出处：《临床麻醉学杂志》1996年01期

【摘要】：观察了17例胃癌合并糖尿病病人围麻醉期血清胰岛素、皮质醇和血糖变化,以及术中输入平衡盐液时血浆电解质的变化。结果表明,胃癌合并糖尿病病人采用神经安定-安氟醚麻醉,血清胰岛素和皮质醇围麻醉期没有明显变化,而血糖随着手术时间延长逐渐增高,麻醉后90min和术毕显著高于麻醉前(P0.01),说明神经安定-安氟醚麻醉虽然能使糖尿病病人术中血清胰岛素和皮质醇平稳,但不能抑制手术应激所致的血糖增高。术中输入平衡盐液血浆电解质无明显改变,认为平衡盐液可补充功能性细胞外液,降低血液粘滞性,改善组织灌流,纠正酸中毒,有利于糖尿病病人恢复。
[Abstract]:The changes of serum insulin, cortisol and blood glucose in 17 patients with gastric cancer complicated with diabetes mellitus during anesthesia and the changes of plasma electrolytes during intraoperative infusion of balanced salt solution were observed. Patients with gastric cancer complicated with diabetes were anesthetized with neurodiazepam-enflurane. The serum insulin and cortisol did not change during the perianaesthesia period, but the blood glucose gradually increased with the operation time prolonged. The levels of 90min and cortisol at the end of anesthesia were significantly higher than those before anesthesia (P 0.01), which indicated that neuro-diazepam enflurane anesthesia could stabilize serum insulin and cortisol in diabetic patients during operation. But it can not inhibit the increase of blood glucose caused by operative stress. There is no obvious change of plasma electrolyte in intraoperative infusion of balanced salt solution. It is considered that balanced salt solution can supplement functional extracellular fluid, reduce blood viscosity, improve tissue perfusion, and correct acidosis. It is beneficial to the recovery of diabetic patients.
【作者单位】：白求恩医科大学第三临床学院中日联谊医院麻醉科白求恩医科大学第三临床学院中日联谊医院麻醉科白求恩医科大学第三临床学院中日联谊医院麻醉科白求恩医科大学第三临床学院中日联谊医院麻醉科长春市第二人民医院麻醉科
【分类号】：R614

【参考文献】