右美托咪定在悬雍垂腭咽成形术后麻醉苏醒期的镇静效果观察

发布时间：2018-04-29 12:06

本文选题：右美托咪定 + 悬雍垂腭咽成形术　；参考：《中国医药科学》2016年19期

【摘要】：目的观察悬雍垂腭咽成形术(UPPP)中右美托咪定对术后镇静效果。方法 2014年10月~2015年12月笔者所在医院阻塞性睡眠呼吸暂停综合征(OSAS)全麻下行UPPP的患者60例,将患者随机方式分为对照组(S组)和右美托咪定组(D组),每组30例。D组静脉输注右美托咪定在手术结束前30min,0.5μg/kg为注射剂量,持续注射15min,S组输注生理盐水。记录各组血液动力学变化及术后躁动及疼痛程度。结果 D组拔管时、拔管后心率和平均动脉低于S组;D组中苏醒期躁动发生率显著低于S组;D组拔管后5min和术后24h VAS评分低于S组,吗啡使用人数也少于S组,差异均有统计学意义(P0.05)。结论应用右美托咪定在UPPP手术中可以维护患者麻醉苏醒期间血流动力学趋稳定,并明显减少苏醒期的躁动且镇痛效果良好。
[Abstract]:Objective to observe the sedation effect of right metoimidine in uvulopalatopharyngoplasty (UPPP) after operation. Methods from October 2014 to December 2015, 60 patients with obstructive sleep apnea syndrome (OSAS) were treated with UPPP under general anesthesia. The patients were randomly divided into control group (S group) and dexmetomidine group (group D). 30 patients in group D were given dexmetomidine 30 minutes before the end of operation. The dosage of dexmetomidine was 0.5 渭 g/kg before the end of operation, and normal saline was continuously injected into group S for 15 minutes. Hemodynamic changes and postoperative restlessness and pain were recorded. Results during extubation, the heart rate and mean arterial restlessness in group D were significantly lower than those in group S (P < 0.05). The 5min and VAS scores in group D were significantly lower than those in group S and the number of morphine users was also lower than that in group S. The difference was statistically significant (P 0.05). Conclusion the use of dexmetidine in UPPP surgery can maintain hemodynamic stability during anaesthesia recovery, reduce restlessness during anaesthesia, and have a good analgesic effect.
【作者单位】：广东省佛山禅城华南耳鼻咽喉专科医院麻醉科;
【分类号】：R614

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