甲磺酸罗哌卡因与盐酸罗哌卡因硬膜外麻醉后的临床疗效及动力学分析

发布时间：2018-05-01 13:00

本文选题：甲磺酸罗哌卡因 + 盐酸罗哌卡因　；参考：《中国现代医生》2016年02期

【摘要】：目的分析甲磺酸罗哌卡因与盐酸罗哌卡因硬膜外麻醉后的临床疗效及动力学。方法随机选取我院2012年8月~2015年8月收治的80例择期行下腹部手术患者,依据随机数字表法分为研究组(n=40)和对照组(n=40)。研究组给予甲磺酸罗哌卡因硬膜外麻醉,对照组给予盐酸罗哌卡因硬膜外麻醉。结果研究组的HR水平显著低于对照组(P0.05),MAP、Sp O_2水平均显著高于对照组(P0.05),感觉阻滞、运动阻滞起效时间均显著短于对照组(P0.05),阻滞时间均显著长于对照组(P0.05),但两组患者术中及术后不良反应发生率22.5%(9/40)、32.5%(13/40)之间的差异无统计学意义(P0.05)。结论甲磺酸罗哌卡因较盐酸罗哌卡因硬膜外麻醉后的临床疗效好,血流动力学稳定。
[Abstract]:Objective to analyze the clinical efficacy and kinetics of ropivacaine mesylate and ropivacaine hydrochloride after epidural anesthesia. Methods from August 2012 to August 2015, 80 patients undergoing elective lower abdominal surgery in our hospital were randomly divided into study group (n = 40) and control group (n = 40). The study group was given epidural anesthesia of ropivacaine mesylate and the control group was given epidural anesthesia of ropivacaine hydrochloride. Results the level of HR in the study group was significantly lower than that in the control group (P 0.05), and the level of MAPSpO _ 2 in the study group was significantly higher than that in the control group (P 0.05). The onset time of motor block was significantly shorter than that of control group (P 0.05), and the time of block was significantly longer than that of control group (P 0.05). However, the incidence of adverse reactions during and after operation in the two groups was 22.5 / 40 and 32.5 / 40 respectively. There was no significant difference between the two groups (P 0.05). Conclusion ropivacaine mesylate is more effective than ropivacaine hydrochloride in epidural anesthesia and its hemodynamics is stable.
【作者单位】：新疆维吾尔自治区塔城市人民医院麻醉科;
【分类号】：R614.42

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