小剂量右美托咪定治疗麻醉诱导后阴茎勃起的效果观察

发布时间：2018-05-03 04:39

本文选题：右美托咪定 + 小剂量　；参考：《山东医药》2016年18期

【摘要】：目的观察小剂量右美托咪定对麻醉诱导后阴茎勃起的治疗效果。方法选择42例拟行尿道手术的男性患者,术中均出现麻醉诱导后阴茎勃起。随机分为观察组和对照组各21例,分别予以咪达唑仑0.25 mg/(kg·h)、盐酸右美托咪定0.5μg/(kg·h)静脉泵注。记录治疗后两组阴茎勃起持续时间,患者阴茎勃起后观察两组治疗前后平均动脉压(MAP)、心率(HR)及血氧饱和度(Sp O2)变化;观察两组麻醉苏醒时间以及术中呼吸抑制、术后意识障碍、恶心呕吐等不良反应发生情况,计算不良反应发生率。结果两组患者均成功完成手术。治疗后观察组阴茎勃起持续时间短于对照组,P0.05。与治疗前比较,观察组和对照组MAP和HR均降低,P均0.05;治疗后观察组MAP和HR均低于对照组,P均0.05。观察组麻醉苏醒时间、不良反应发生率均低于对照组,P均0.05。结论小剂量右美托咪定治疗麻醉诱导后阴茎勃起效果较好,可维持患者血流动力学稳定,缩短患者术后患者苏醒时间,不良反应较少。
[Abstract]:Objective to observe the effect of low dose dexmetomidine on penile erection induced by anesthesia. Methods 42 cases of male patients undergoing urethral surgery were selected. They were randomly divided into observation group (n = 21) and control group (n = 21) by intravenous injection of midazolam 0.25 mg/(kg / h and dexmetomidine hydrochloride 0.5 渭 g/(kg / h respectively. After treatment, the duration of penile erection was recorded, the mean arterial pressure (MAPV), heart rate (HRT) and blood oxygen saturation (SPO _ 2) before and after treatment were observed, the recovery time of anesthesia, the inhibition of respiration during operation, and the disturbance of consciousness after operation were observed. Incidence of adverse reactions such as nausea and vomiting was calculated. Results the operation was successfully completed in both groups. After treatment, the duration of penile erection in the observation group was shorter than that in the control group (P 0.05). Compared with before treatment, the MAP and HR of the observation group and the control group were decreased by 0.05, and the MAP and HR of the observation group were lower than those of the control group (P < 0.05). The anaesthesia recovery time and adverse reaction rate in the observation group were lower than those in the control group (P < 0.05). Conclusion low dose dexmetomidine is effective in the treatment of penile erectile after anesthesia induction, which can maintain hemodynamic stability, shorten the recovery time of patients after operation, and have fewer adverse reactions.
【作者单位】：重庆三峡中心医院;
【分类号】：R614

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