全身麻醉后下呼吸道感染患者病原菌的分布及其对抗菌药物的耐药性分析

发布时间：2018-05-07 20:20

本文选题：抗菌药物 + 耐药性　；参考：《抗感染药学》2016年05期

【摘要】：目的:分析全身麻醉后下呼吸道感染患者病原菌的分布及其对抗菌药物的耐药性。方法:选取2011年—2015年间收治的外科全麻手术患者600例临床资料,分析发生下呼吸道感染患者致病菌的临床分布及其抗菌药物的使用。结果:收治的600例全麻手术患者中,36例患者发生下呼吸道感染情况,其中以神经外科手术患者的感染率为最高,其次依序为胸部心血管外科、胃肠道消化外科、骨外科、泌尿外科及其他感染;36例感染患者经细菌培养分离出40株病原菌,主要以革兰阴性菌24株(60.00%)、革兰阳性菌14株(35.00%)和其他病原菌2株(5.00%);革兰阴性菌对考拉宁、万古霉素及头孢曲松钠具有较低的耐药性,革兰阳性菌对亚胺培南、美罗培南及阿米卡星具有较低的耐药性。结论:对于全麻后下呼吸道感染患者应根据其感染的相关因素对症治疗,并根据其药敏实验结果合理使用抗生素。
[Abstract]:Objective: to analyze the distribution of pathogens and their resistance to antibiotics in patients with lower respiratory tract infection after general anesthesia. Methods: the clinical data of 600 patients undergoing general anesthesia from 2011 to 2015 were selected to analyze the clinical distribution of pathogenic bacteria and the use of antimicrobial agents in patients with lower respiratory tract infection. Results: among the 600 patients undergoing general anesthesia, 36 cases had lower respiratory tract infection. The infection rate of neurosurgery was the highest, followed by thoracic cardiovascular surgery, gastrointestinal digestive surgery and bone surgery. Forty strains of pathogenic bacteria were isolated from 36 cases of urinary surgery and other infected patients, mainly by Gram-negative bacteria (24 strains), Gram-positive bacteria (14 strains) and other pathogens (2 strains). Vancomycin and ceftriaxone sodium showed lower resistance to imipenem, meropenem and amikacin, while Gram-positive bacteria had lower resistance to imipenem, meropenem and amikacin. Conclusion: patients with lower respiratory tract infection after general anesthesia should be treated according to the related factors of their infection, and antibiotics should be used reasonably according to the results of drug sensitivity test.
【作者单位】：抚州市第一人民医院麻醉科;
【分类号】：R614

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