瑞芬太尼、芬太尼在腹腔镜手术麻醉中的临床应用效果

发布时间：2018-05-07 21:25

本文选题：腹腔镜手术 + 手术麻醉　；参考：《中外医学研究》2016年36期

【摘要】：目的:对比分析瑞芬太尼与芬太尼应用于腹腔镜手术麻醉中的麻醉效果和安全性。方法:选取86例在笔者所在医院行腹腔镜手术患者作为研究对象,对其临床资料进行回顾性分析。根据麻醉药物将其分为A组(45例)和B组(41例),其分别应用瑞芬太尼和芬太尼进行麻醉诱导和维持。比较两组患者血流动力学变化情况、麻醉效果以及不良反应发生情况。结果:两组患者诱导后1 min以及插管后1、2和5 min的HR和MAP与诱导前比较,差异均有统计学意义(P0.05),而术后5 min则恢复至诱导前水平;且插管后1、2和5 min两组患者HR和MAP比较,差异均有统计学意义(P0.05);而A组患者诱导前后两项指标变化与B组相比更为稳定。A组患者自主呼吸恢复时间、睁眼时间、拔管时间和离开恢复室时间均明显短于B组,差异均有统计学意义(P0.05);A组呼吸道梗阻或屏气及拔管后Sp O290%的发生率也明显低于B组,但A组患者术后躁动发生率明显高于B组,差异均有统计学意义(P0.05)。结论:瑞芬太尼应用于腹腔镜手术患者的麻醉中有助于患者维持更为平稳的血流动力学变化,且患者术后苏醒快,苏醒质量好,安全性高,具有较高的临床应用价值。
[Abstract]:Objective: To compare and analyze the anesthetic effect and safety of remifentanil and fentanyl used in laparoscopic anesthesia. Methods: a retrospective analysis was made in 86 cases of laparoscopic surgery in my hospital. The clinical data were analyzed retrospectively. According to narcotic drugs, they were divided into group A (45 cases) and group B (41 cases), which were applied respectively. Remifentanil and fentanyl were induced and maintained. Hemodynamic changes, anesthetic effects and adverse reactions were compared between the two groups. Results: the differences were statistically significant between the two groups of patients after induction of 1 min and HR and MAP of 1,2 and 5 min after intubation (P0.05), while 5 min recovered to induction after operation. The difference of HR and MAP in 1,2 and 5 min two groups after intubation was statistically significant (P0.05), while the changes of two indexes before and after induction in group A were more stable than those in the B group, and the time of eye opening, extubation time and leaving recovery room were significantly shorter than those in the group of B (P0.). The difference was statistically significant (P0.). 05): the incidence of Sp O290% after respiratory obstruction or breath holding and extubation in group A was also significantly lower than that in group B, but the incidence of postoperative restlessness in group A was significantly higher than that in group B (P0.05). Conclusion: the application of remifentanil to patients with laparoscopic surgery could help patients maintain more stable hemodynamic changes and patients. The postoperative recovery is fast, the quality of recovery is good, the safety is high, and it has high clinical application value.

【作者单位】：滨海县第二人民医院;
【分类号】：R614

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