异丙酚联合瑞芬太尼用于颅内动脉瘤夹闭术麻醉效果观察

发布时间：2018-05-11 01:42

本文选题：颅内动脉瘤 + 动脉瘤夹闭术　；参考：《山东医药》2015年48期

【摘要】：目的探讨异丙酚联合瑞芬太尼用于颅内动脉瘤夹闭术的麻醉效果。方法将84例行颅内动脉瘤夹闭术的患者随机分为对照组和观察组各42例。观察组给予异丙酚联合瑞芬太尼静脉麻醉,对照组予异丙酚联合异氟醚复合麻醉。比较两组血压、HR、术后恢复情况、术后躁动及再出血率等指标。结果两组动脉瘤夹闭时收缩压、舒张压、平均动脉压均较麻醉前及气管拔管后降低(P均0.05)。观察组自主呼吸恢复时间、呼唤后睁眼时间、定向力恢复时间、气管拔管时间、离开手术室时间均明显短于对照组(P均0.01)。观察组及对照组术后1天躁动发生率分别为4.8%(2/42)、30.9%(13/42),P0.01;术后3天内再出血发生率分别为0、14.0%,P0.05。结论异丙酚联合瑞芬太尼静脉麻醉用于颅内动脉瘤夹闭术的降压效果与异丙酚联合异氟醚静吸复合麻醉相近,但术后复苏快、再出血率低。
[Abstract]:Objective to investigate the anesthetic effect of propofol combined with remifentanil in intracranial aneurysm clipping. Methods Eighty-four patients undergoing intracranial aneurysm clipping were randomly divided into control group (n = 42) and observation group (n = 42). The observation group received propofol combined with remifentanil intravenous anesthesia while the control group received propofol combined with isoflurane anesthesia. The blood pressure HRs, postoperative recovery, postoperative restlessness and rebleeding rate were compared between the two groups. Results the systolic blood pressure, diastolic pressure and mean arterial pressure in both groups were lower than those before anesthesia and after tracheal extubation. The recovery time of spontaneous respiration, the time of eye opening after call, the time of recovery of directional force, the time of tracheal extubation and the time of leaving the operating room in the observation group were significantly shorter than those in the control group (P < 0.01). The incidence of restlessness in the observation group and the control group on the first day after operation was 4.810 / 42 / 30.9, respectively, and the incidence of recurrent bleeding within 3 days after operation was 0 / 14.0 / (P0.05), respectively. Conclusion the antihypertensive effect of propofol combined with remifentanil for intracranial aneurysm clipping is similar to that of propofol combined with isoflurane combined with intravenous anesthesia.
【作者单位】：湖北省中西医结合医院;
【分类号】：R614

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