不同麻醉方法下宫颈癌手术患者术前、中、后外周血炎症相关细胞因子水平观察

发布时间：2018-05-19 03:08

本文选题：不同麻醉方法 + 宫颈癌　；参考：《中国医药导刊》2016年08期

【摘要】：目的:探究不同麻醉方法下宫颈癌患者手术前、中、后外周血炎症相关细胞因子水平观察。方法:选取我院接受的宫颈癌患者80例,随机分成观察组与对照组。观察组给予吸入全麻醉,对照组给予静脉麻醉,对比两组患者手术前、中、后外周血炎症相关细胞因子的水平。结果:在手术后30min与手术后24h,两组血浆IL-8的水平分别高于手术前与手术中;IL-17在手术中与手术后30min的水平均出现显著下降,但在手术后的24h的水平相较于手术前是所有上升的。观察组的IL-17的水平明显高于对照组:两组ICAM-1的水平在手术前与手术中均有显著下降。结论:手术中,不同麻醉方式引发的外周血炎症反应相似;术后24h后吸入全麻醉方式的IL-17的水平会高于静脉麻醉。
[Abstract]:Objective: to investigate the levels of inflammatory cytokines in peripheral blood of cervical cancer patients before, during and after operation under different anesthesia methods. Methods: 80 patients with cervical cancer received in our hospital were randomly divided into observation group and control group. The observation group was given general inhalation anesthesia, the control group was given intravenous anesthesia, and the levels of inflammatory cytokines in peripheral blood were compared before, during and after operation. Results: after 30min and 24 h after operation, the level of plasma IL-8 in both groups was significantly lower than that before and during operation. However, the level of IL-17 in 24 hours after operation was higher than that before operation. The level of IL-17 in the observation group was significantly higher than that in the control group: the level of ICAM-1 in both groups decreased significantly before and during operation. Conclusion: the inflammatory reaction of peripheral blood induced by different anesthetic methods is similar, and the level of IL-17 inhaled in general anesthesia is higher than that in intravenous anesthesia 24 hours after operation.
【作者单位】：陕西省宝鸡市妇幼保健院麻醉科;
【分类号】：R737.33;R614

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