喷他佐辛对老年患者全麻芬太尼抑制插管反应的影响

发布时间：2018-05-27 18:34

本文选题：喷他佐辛 + 芬太尼　；参考：《中国老年学杂志》2015年03期

【摘要】：目的观察喷他佐辛在老年患者全身麻醉诱导期对芬太尼抑制插管应激反应的影响。方法拟行全麻下腹腔镜胆囊切除术老年患者100例,随机分为喷他佐辛组(P组)和对照组(C组)各50例。常规全身麻醉诱导前P组静脉注射喷他佐辛30 mg,C组静脉注射同体积的生理盐水,5 min后进行全麻诱导,达到插管条件后行气管插管,观察并记录诱导前(T0)、诱导时(T1)、诱导后3 min(T2)、插管即刻(T3)、插管后3 min(T4)的平均动脉压(MAP)、心率(HR)的变化。结果 T2与T0比较,两组MAP、HR均下降(P0.05);T3时刻C组MAP、HR均显著高于T0时刻(P0.05),P组MAP、HR与T0时刻无显著差异(P0.05),并且P组MAP、HR低于C组(P0.05)。结论老年患者全麻诱导前静脉注射喷他佐辛30 mg可加强芬太尼抑制插管反应的作用。
[Abstract]:Objective to observe the effect of pentazol on the stress response of fentanyl in the induction of general anesthesia in elderly patients. Methods 100 elderly patients undergoing laparoscopic cholecystectomy under general anesthesia were randomly divided into two groups: control group (n = 50) and control group (n = 50). Before general anesthesia induction, group P was injected with tazosin 30 mg / g group intravenously for 5 min after intravenous injection of the same volume of normal saline to induce general anesthesia. Tracheal intubation was performed after the condition of intubation was reached. The changes of mean arterial pressure (MAPP) and heart rate (HRR) were observed and recorded before induction, during induction, 3 min after intubation and 3 min after intubation. Results compared with T0, the MAPHR of group C was significantly higher than that of group C at T _ 0 and T _ 0. There was no significant difference between group T _ 2 and T _ 0, and the MAPHR of group P was lower than that of group C (P 0.05). Conclusion intravenous injection of tazosin 30 mg before induction of general anesthesia in elderly patients can enhance the inhibitory effect of fentanyl on intubation response.
【作者单位】：吉林大学白求恩第一医院麻醉科;
【分类号】：R614.2

【参考文献】