丙泊酚和依托咪酯分别联合舒芬太尼应用于内镜下息肉摘除术120例麻醉效果评价

发布时间：2018-05-29 15:43

本文选题：丙泊酚 + 依托咪酯　；参考：《上海医药》2016年23期

【摘要】：目的 :比较丙泊酚和依托咪酯分别联合舒芬太尼应用于内镜下息肉摘除术的麻醉效果及不良反应。方法 :选取我院内镜下息肉摘除术患者120例,ASA I-II级,随机分为丙泊酚联合舒芬太尼组(A组)60例,依托咪酯联合舒芬太尼组(B组)60例,监测并记录手术前、中、后的血流动力学变化;记录麻醉前(T0)、给药后入镜前(T1)、入镜后2 min(T2)、入镜后5 min(T3)、检查结束(T4)、苏醒时(T5)的心率,平均动脉压、血氧饱和度以及苏醒时间、不良事件以及术后并发症的发生率。结果 :A组在T1、T2、T3、T4时HR、MAP下降明显(P0.05)。B组的HR、MAP在各时间点比较差异无统计学意义(P0.05)。结论 :内镜下息肉摘除术术前用依托咪酯联合舒芬太尼麻醉,对血压、心率影响小,不良反应发生少,安全性高,推荐临床使用。
[Abstract]:Aim: to compare the anesthetic effects and side effects of propofol and etomidate combined with sufentanil in endoscopic polyposectomy. Methods: one hundred and twenty patients with I-II grade were randomly divided into propofol and sufentanil group (n = 60), etomidate combined with sufentanil group (n = 60) and sufentanil group (n = 60). The changes of hemodynamics were recorded before anaesthesia, before anesthesia, before administration, after administration, and 2 min after operation, and 5 min after operation. Heart rate, mean arterial pressure, saturation of blood oxygen, and recovery time were recorded at the end of T4 and T5), and the changes of hemodynamics were recorded before and after anaesthesia, and 2 mins after the operation, and 5 min after the operation, the changes of hemodynamics were recorded, and the mean arterial pressure, blood oxygen saturation, and recovery time were recorded. Incidence of adverse events and postoperative complications. Results there was no significant difference in HRMAP between group A and group B at different time points (P 0.05), and there was no significant difference in HRMAP between two groups at different time points (P 0. 05%, P 0. 05%, P 0. 05%, P 0. 05%, P 0. 05%, P 0. 05, P 0. 05). Conclusion: Etomidate combined with sufentanil anesthesia before endoscopic polyp excision has little effect on blood pressure and heart rate, less adverse reactions and high safety. It is recommended for clinical use.
【作者单位】：上海市同济医院;
【基金】：上海市药学会科研项目(2014-YY-02-14)
【分类号】：R614

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