不同剂量咪达唑仑用于腰硬联合麻醉的临床疗效观察

发布时间：2018-06-02 11:07

本文选题：咪达唑仑 + 腰硬联合麻醉　；参考：《医疗装备》2016年14期

【摘要】：目的探讨不同剂量咪达唑仑用于腰硬联合麻醉进行腹部手术的临床疗效。方法将2012年8月至2014年8月收治的择期进行腹部手术的120例患者随机分为A、B、C三组,每组患者40例,分别以0.05,0.10,0.15 mg/kg注射咪达唑仑。对注射不同剂量咪达唑仑后进行腹部手术患者的镇静、遗忘及不良反应、临床疗效进行记录观察。结果 A组患者镇静效果不全率最高;C组镇静过度率最高;A组患者遗忘率最低,差异有统计学意义(P0.05);而B组与C组患者间遗忘率比较差异无统计学意义(P0.05)。C组患者临床不良反应发生率最高,差异有统计学意义(P0.05);A组与B组患者不良反应发生率比较差异无统计学意义(P0.05)。结论腰硬联合麻醉用于腹部手术静脉注射咪达唑仑为0.10 mg/kg时镇静效果最好,不良反应发生率较低,完全遗忘率较高。
[Abstract]:Objective to investigate the clinical effect of midazolam at different doses for abdominal surgery under combined spinal-epidural anesthesia. Methods from August 2012 to August 2014, 120 patients undergoing abdominal surgery were randomly divided into three groups, 40 patients in each group were injected with midazolam with 0.05g 0.100.100.15 mg/kg. The sedation, amnesia and adverse reactions of patients undergoing abdominal surgery after different doses of midazolam were recorded and observed. Results Group A had the highest rate of incomplete sedation and the group C had the highest rate of excessive sedation and the group A had the lowest forgetting rate. There was no significant difference in amnesia rate between group B and group C, and the incidence of clinical adverse reactions was the highest in group B and group C, and there was no significant difference in the rate of amnesia between group B and group C. There was no significant difference in the incidence of adverse reactions between group A and group B (P 0.05). Conclusion combined spinal-epidural anesthesia has the best sedative effect when intravenous midazolam injection is 0.10 mg/kg, the incidence of adverse reactions is lower, and the complete amnesia rate is higher.
【作者单位】：湖北省襄阳市谷城县中医院麻醉科;
【分类号】：R614

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