碳酸利多卡因表面麻醉在纤维支气管镜检查中的应用探讨

发布时间：2018-06-06 08:52

本文选题：碳酸利多卡因 + 盐酸利多卡因　；参考：《广西医科大学》2014年硕士论文

【摘要】：目的：探讨碳酸利多卡因(LC)在纤维支气管镜(FB)检查中的应用价值。方法：选取在我院行FB检查患者126例,随机分为观察组66例和对照组60例,在FB检查过程中分别使用1.73%LC和2%盐酸利多卡因(LH)行表面麻醉,每例患者使用药物总剂量均为14m1。使用多参数监护仪在FB检查过程中监测患者指脉氧(SPO2)、心率(HR)及呼吸频率(RR)的变化情况,并计算指脉氧变异率(SPO2-VR)、心率变异率(HR-VR)及呼吸频率变异率(RR-VR),记录检查时间及评价麻醉效果,并比较两组间各参数的差异性。结果：1、观察组及对照组的SP02-VR分别为4.17±4.54、5.62±5.37(P=0.1030.05),差异无统计学意义。2、观察组及对照组的HR-VR分别为2.54±1.36、2.91±1.5(P=0.147＞0.05),差异无统计学意义。3、观察组及对照组的RR-VR分别为4.09±1.79、4.98±1.97(P=0.0090.05),差异有统计学意义。4、观察组及对照组的FB检查时间分别为8.59±3.73、8.55±3.27(P=0.9480.05),差异无统计学意义。5、观察组的麻醉效果优于对照组(P0.05),差异有统计学意义。结论：研究表明在FB检查过程中,LC的麻醉效能优于LH,使用LC的患者呼吸较平稳,建议在FB检查中使用LC进行表面麻醉。
[Abstract]:Objective: to evaluate the value of lidocaine carbonate (LC) in fiberoptic bronchoscopy (FB). Methods: 126 patients with FB in our hospital were randomly divided into observation group (n = 66) and control group (n = 60). 1.73%LC and lidocaine hydrochloride (2% lidocaine hydrochloride) were used in the course of FB examination respectively. The total dose of each patient was 14ml. Multiparameter monitor was used to monitor the changes of SPO _ 2 (HRR) and respiratory frequency (RR) during FB examination, and to calculate the variability rate of phalanx (SPO _ 2-VRN), HR-VRR (HR-VRR) and RR-VRN, and to record the time of examination and evaluate the anesthetic effect. The differences of parameters between the two groups were compared. Results the SP02-VR of the observation group and the control group were 4.17 卤4.54 卤4.54 卤5.62 卤5.37, respectively, with no significant difference. The HR-VR of the observation group and the control group were 2.54 卤1.36 卤2.91 卤1.5(P=0.147 > 0.05, respectively. The RR-VR of the observation group and the control group were 4.09 卤1.794.98 卤1.97 P0. 05, respectively. The difference was statistically significant. The time of FB in the observation group and the control group was 8.59 卤3.73 卤8.55 卤3.27 P0. 948. 05, respectively. There was no significant difference between the observation group and the control group. The anesthetic effect of the observation group was better than that of the control group (P 0. 05), and the difference was statistically significant. Conclusion: the anaesthesia efficacy of LC in FB examination is better than that in LH.The patients who use LC have stable breathing. It is suggested that LC should be used for superficial anesthesia in FB examination.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R614

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