不同麻醉药物配伍对老年腹腔镜手术术后认知影响

发布时间：2018-06-16 16:53

本文选题：麻醉药物 + 配伍方式　；参考：《中国实用医药》2016年22期

【摘要】：目的探讨不同麻醉药物配伍对老年腹腔镜手术术后认知的影响。方法 52例行腹腔镜手术治疗的老年患者,根据麻醉方式的不同将其分为A组(32例)和B组(20例)。B组采用七氟醚、瑞芬太尼联合右美托咪定麻醉药物配伍,A组采用异氟醚、芬太尼联合咪唑安定等药物配伍,比较两组术后麻醉苏醒状况及简易精神状态量表(MMSE)评分。结果两组定向力恢复时间比较差异具有统计学意义(P0.05)。术后2、12、24 h A组患者MMSE评分分别为(24.1±1.9)、(26.9±2.2)、(27.8±1.9)分,均明显高于B组的(20.3±1.2)、(22.1±1.4)、(25.3±1.0)分(P0.05)。结论七氟醚、瑞芬太尼联合右美托咪定等药物配伍麻醉方式对老年腹腔镜手术患者术后认知功能恢复期情况明显优于异氟醚、芬太尼联合咪唑安定等药物配伍,可在临床推广。
[Abstract]:Objective to investigate the effect of different anesthetic combinations on the postoperative cognition of elderly patients undergoing laparoscopic surgery. Methods 52 elderly patients undergoing laparoscopic surgery were divided into group A (n = 32), group B (n = 20) and group B (n = 20) treated with sevoflurane. Remifentanil combined with dexmetomidine was used in group A, and isoflurane was used in group A. Fentanyl combined with midazolam and other drugs were used to compare the recovery of anesthesia and the MMSE score. Results there was significant difference in the recovery time of directional force between the two groups (P 0.05). The MMSE scores in group A were 24.1 卤1.9 and 26.9 卤2.2 respectively, which were significantly higher than those in group B (20.3 卤1.2) and 25.3 卤1.0 (P 0.05) respectively. Conclusion the combination of sevoflurane, remifentanil and dexmetomidine is superior to isoflurane in the recovery of cognitive function in elderly patients undergoing laparoscopic surgery. Fentanyl combined with midazolam can be popularized in clinic.
【作者单位】：河南省许昌市中心医院南区医院麻醉科;
【分类号】：R614

【相似文献】