右美托咪啶预防儿童七氟醚麻醉苏醒期躁动效果的观察

发布时间：2018-06-20 12:07

本文选题：七氟醚麻醉 + 右美托咪啶　；参考：《河南外科学杂志》2016年01期

【摘要】：目的观察应用右美托咪啶预防儿童七氟醚麻醉苏醒期躁动的效果。方法将56例接受七氟醚麻醉手术的患儿随机分为2组,每组28例。观察组:麻醉诱导后静脉泵注右美托咪定注射液0.5μg/kg(稀释到15 m L),10~20 min注完后开始手术。对照组:麻醉诱导后手术开始前泵注15 m L生理盐水。比较2组患儿右美托咪啶或生理盐水注射前(T0)、注射5 min后(T1)、患儿苏醒睁眼时间点(T2)及拔管5 min后(T3)心率、血压变化和麻醉后的苏醒时间、躁动情况等。结果对照组T2和T3时点的NAP和HR较T0明显升高,差异有统计学意义(P0.05);与对照组比较,观察组T2和T3时间点MAP明显降低,同时T1、T2和T3时间点HR明显降低,差异均有统计学意义(P0.05)。观察组患儿苏醒期躁动发生率低于对照组,苏醒时间长于于对照组,2组比较差异具有统计学意义(P0.05)。结论麻醉诱导后手术开始前应用右美托咪啶,在儿童七氟醚麻醉时能较好维持血流动力学的平稳,降低苏醒期的躁动发生率。
[Abstract]:Objective to observe the effect of dexmetidine on prevention of restlessness during sevoflurane anesthesia in children. Methods 56 children undergoing sevoflurane anesthesia were randomly divided into 2 groups with 28 cases in each group. Observation group: after anesthesia induction, intravenous injection of dexmetomidine 0.5 渭 g / kg (diluted to 15 mL / kg 1020 min) was performed. Control group: 15 mL saline was injected by pump before operation after anesthesia induction. The changes of heart rate, blood pressure, recovery time after anesthesia and restlessness were compared between the two groups before dexmetidine or normal saline injection, 5 min after injection, after 5 min, the recovery time was T2), and 5 min after extubation, the heart rate, blood pressure, recovery time after anesthesia, restlessness, and so on were compared between the two groups. Results compared with the control group, the map at T2 and T3 time points in the control group was significantly lower than that in the control group (P 0.05), and the HR at T 1 T 2 and T 3 time points was significantly lower than that in the control group (P 0.05). The incidence of restlessness in the observation group was lower than that in the control group, and the recovery time was longer than that in the control group (P 0.05). Conclusion before anesthesia induction, dexmetidine can maintain hemodynamic stability and reduce restlessness during sevoflurane anesthesia in children.
【作者单位】：河南汝州市第二人民医院麻醉科;
【分类号】：R726.1

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