针刺联合椎管内麻醉的辅助镇静效果分析

发布时间：2018-07-07 20:11

本文选题：针刺 + 咪达唑仑　；参考：《中华中医药学刊》2015年05期

【摘要】：目的:观察针刺联合椎管内麻醉用于辅助镇静的有效性和安全性。方法:对ASA分级为I级或II级的320例经明确要采用椎管内麻醉的手术患者随机分为实验组和对照组两组,每组分别为160例。实验组患者针刺联合静脉注射咪达唑仑4μg/kg辅助镇静,对照组患者静脉注射咪达唑仑4μg/kg辅助镇静。记录两组给药前(T0),给药后10 min(T1),20 min(T2),30 min(T3)和患者苏醒后(T4)各时点的RR、MAP、HR、SPO2以及OAA/S评分情况,以及手术过程中两组患者出现的不良反应发生率。结果:对照组的患者在T2和T3时间点的RR和SPO2与用药前相比明显降低(P0.05);实验组和对照组两组研究对照在T3时间点的OAA/S分级评分明显低于用药前的评分(P0.05)。在手术过程中对照组患者出现呼吸抑制、上呼吸道梗阻和恶心呕吐等不良反应的发生率明显高于实验组(P0.05)。结论:针刺联合椎管内麻醉采用咪达唑仑比使用依托咪酯具有较好的辅助镇静作用,安全性高,呼吸抑制程度较轻。
[Abstract]:Objective: to observe the efficacy and safety of acupuncture combined with intraspinal anesthesia for auxiliary sedation. Methods: 320 patients with ASA grade I or II were randomly divided into experimental group (n = 160) and control group (n = 160). Acupuncture combined with midazolam 4 渭 g/kg was used to assist sedation in the experimental group and midazolam 4 渭 g/kg in the control group. Before administration (T 0), 10 min (T 1) and 20 min (T 2) 30 min (T 3) and after recovery (T 4), the RRX MAPHR-SPO 2 and OAA / S scores were recorded in both groups, as well as the incidence of adverse reactions in the two groups during the operation. Results: the RR and SPO _ 2 of the patients in the control group at T2 and T3 time points were significantly lower than those before treatment (P0.05), while the OAA / P scores of the experimental group and the control group at T3 time point were significantly lower than those before treatment (P0.05). The incidence of respiratory depression, upper respiratory obstruction and nausea and vomiting in the control group was significantly higher than that in the experimental group (P0.05). Conclusion: midazolam combined with spinal canal anesthesia has better auxiliary sedation effect, higher safety and less respiratory inhibition than etomidate.
【作者单位】：宁波市鄞州区人民医院麻醉科;
【分类号】：R614

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