2%利多卡因喷雾剂联合复方利多卡因乳膏在老年患者支气管插管全麻中的应用
发布时间:2018-08-28 20:51
【摘要】:目的观察2%利多卡因喷雾剂联合复方利多卡因乳膏气管黏膜表面麻醉在老年患者支气管插管全麻中应用的安全性及可行性。方法将120例择期行支气管插管全麻的老年患者分为4组,每组30例。Ⅰ组:将石蜡油均匀涂于支气管导管的套囊及前端;Ⅱ组:麻醉前10 min用2%利多卡因溶液喷雾患者的咽喉部,再将石蜡油均匀涂于支气管导管的套囊及前端;Ⅲ组:将复方利多卡因乳膏均匀涂于支气管导管的套囊及前端;Ⅳ组:麻醉前10 min用2%利多卡因溶液喷雾患者的咽喉部,再将复方利多卡因乳膏均匀涂于支气管导管的套囊及前端。观察并记录4组患者麻醉前(T1)、插管前5 min(T2)、插管时(T3)、插管后5 min(T4)、由仰卧位变侧卧位时(T5)、由侧卧位变仰卧位时(T6)、拔管前5 min(T7)、拔管时(T8)、拔管后5 min(T9)各时点SBP、DBP、HR的变化及术后24 h内咽喉疼痛、声音嘶哑及脑血管意外并发症的发生率。结果与Ⅰ组和Ⅲ组T3、T4、T5时相比,Ⅱ组和Ⅳ组的SBP、DBP、HR明显降低(P0.05);与Ⅰ组和Ⅱ组T6、T8、T9相比,Ⅲ组和Ⅳ组的SBP、DBP、HR明显降低(P0.05)。与Ⅰ组相比,Ⅲ组和Ⅳ组的咽喉痛和声音嘶哑发生率明显降低(P0.05),Ⅰ组出现1例脑血管意外。结论 2%利多卡因喷雾剂和复方利多卡因乳膏联合用于老年患者支气管插管全麻中,可以有效抑制支气管插管和拔管引起的心血管应激反应,减少咽喉疼痛和声音嘶哑发生率,毒性低,安全性高,具有良好的临床应用价值。
[Abstract]:Objective to observe the safety and feasibility of 2% lidocaine spray combined with compound lidocaine cream for tracheal surface anesthesia in elderly patients with bronchial intubation. Methods 120 elderly patients undergoing bronchial intubation general anesthesia were divided into 4 groups (30 cases in each group). Group 鈪,
本文编号:2210580
[Abstract]:Objective to observe the safety and feasibility of 2% lidocaine spray combined with compound lidocaine cream for tracheal surface anesthesia in elderly patients with bronchial intubation. Methods 120 elderly patients undergoing bronchial intubation general anesthesia were divided into 4 groups (30 cases in each group). Group 鈪,
本文编号:2210580
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