七氟烷麻醉与丙泊酚麻醉对腹腔镜直肠癌根治术患者术后肝功能的影响

发布时间：2018-09-10 05:59

【摘要】：目的探讨七氟烷维持麻醉和丙泊酚维持麻醉对腹腔镜直肠癌根治术患者术后肝功能的影响。方法选取本院2014年3~12月行腹腔镜下直肠癌根治术(Dixon术)的60例直肠癌患者作为研究对象,随机分为Pro组和Sev组,各30例。Pro组采用丙泊酚麻醉,Sev组采用七氟烷麻醉。比较两组不同时间点的血压和心率以及乳酸脱氢酶(LDH)、丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、碱性磷酸酶(ALP)和胆红素(TBi L)水平。结果两组的麻醉时间、手术时间、气腹时间和瑞芬太尼总用量比较,差异无统计学意义(P0.05)。两组不同时间点的血压和心率比较,差异无统计学意义(P0.05)。两组术后24、72 h的LDH、AST、ALT、ALP和TBi L水平与术前比较,差异无统计学意义(P0.05)。两组术后24、72 h的LDH、AST、ALT、ALP和TBi L水平比较,差异无统计学意义(P0.05)。结论七氟烷维持麻醉和丙泊酚维持麻醉对腹腔镜下直肠癌根治术(Dixon术)患者的肝功能影响相近。
[Abstract]:Objective to investigate the effect of sevoflurane maintenance anesthesia and propofol maintenance anesthesia on liver function after laparoscopic radical rectal cancer surgery. Methods from March to December 2014, 60 patients with rectal cancer underwent laparoscopic radical resection of rectal cancer (Dixon) were randomly divided into Pro group and Sev group. 30 patients in each group were treated with propofol anesthesia and sev group with sevoflurane anesthesia. The blood pressure, heart rate and the levels of lactate dehydrogenase (LDH), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and bilirubin (TBi L) (TBi L) were compared between the two groups at different time points. Results there was no significant difference in anesthesia time, operation time, pneumoperitoneum time and total remifentanil dosage between the two groups (P0.05). There was no significant difference in blood pressure and heart rate between the two groups at different time points (P0.05). There was no significant difference in LDH,AST,ALT,ALP and TBi L levels between the two groups at 24 h after operation (P0.05). There was no significant difference in LDH,AST,ALT,ALP and TBi L levels between the two groups at 24 h after operation (P0.05). Conclusion the effects of sevoflurane maintenance anesthesia and propofol maintenance anesthesia on liver function of patients undergoing laparoscopic radical resection of rectal cancer (Dixon) are similar.
【作者单位】：广西壮族自治区北流市人民医院麻醉科;
【分类号】：R614;R735.37

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