地佐辛对瑞芬太尼复合麻醉患者术后苏醒期镇痛镇静效果探讨

发布时间：2018-10-29 16:45

【摘要】：目的探讨地佐辛不同给药方式对瑞芬太尼复合麻醉患者术后苏醒期拔管及镇痛镇静效果。方法按照随机数字表法将82例患者均分为肌肉注射组和静脉注射组,两组患者均常规行全麻腹腔镜胆囊切除术,肌肉注射组和静脉注射组患者于手术结束前0.5h分别给予地佐辛肌肉注射和静脉注射,比较两组患者术后苏醒期拔管及镇痛镇静效果。结果肌肉注射组患者麻醉苏醒和拔管时间均明显低于静脉注射组,差异具有显著性(P0.05);肌肉注射组患者苏醒后1h、2h VAS评分均略低于静脉注射组,苏醒时及苏醒后1h、2h SAS评分均略低于静脉注射组,但两组间比较,差异无统计学意义(P0.05);肌肉注射组患者呼吸抑制、恶心呕吐发生率均明显低于静脉注射组,差异具有显著性(P0.05)。结论地佐辛肌肉注射较静脉注射术后苏醒和拔管时间更短,不良反应发生率更低,临床优势明显。时间更短,不良反应发生率更低,临床优势明显。
[Abstract]:Objective to investigate the effects of different administration of dizosin on extubation and analgesia and sedation in patients with remifentanil combined anesthesia. Methods Eighty-two patients were divided into intramuscular injection group and intravenous injection group according to the random number table method. The patients in both groups were routinely treated with laparoscopic cholecystectomy under general anesthesia. The patients in the intramuscular injection group and the intravenous injection group were given dizosin intramuscular injection and intravenous injection 0.5 h before the end of the operation. The effects of extubation and analgesia and sedation were compared between the two groups. Results the time of anesthesia recovery and extubation in the intramuscular injection group was significantly lower than that in the intravenous injection group (P0.05). In the intramuscular injection group, the VAS score at 2 hours after awakening was slightly lower than that in the intravenous injection group, and the SAS score at the time of awakening and 1 hour after awakening was slightly lower than that in the intravenous injection group, but there was no significant difference between the two groups (P0.05). The incidence of respiratory inhibition, nausea and vomiting in the intramuscular injection group was significantly lower than that in the intravenous injection group (P0.05). Conclusion compared with intravenous injection, dizosin intramuscular injection has shorter recovery and extubation time, lower incidence of adverse reactions and obvious clinical advantages. The time is shorter, the incidence of adverse reactions is lower, and the clinical advantages are obvious.
【作者单位】：江西省新余市新钢中心医院;
【分类号】：R614

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