气管插管全麻术后患者下呼吸道感染的危险因素分析

发布时间：2018-11-01 11:23

【摘要】：目的探讨气管插管全麻术患者术后发生下呼吸道感染的危险因素,为控制降低术后感染的发生提供参考依据。方法选取2012年6月-2014年6月住院行气管插管全麻术后发生下呼吸道感染的1 013例患者为研究对象,对发生下呼吸道感染的60例患者进行相关干预治疗,比较感染患者在干预前后的体温、中性粒细胞比例、白细胞总数以及降钙素原(PCT)值;分析患者发生下呼吸道感染的相关因素,并进一步通过多因素logistic回归分析患者发生下呼吸道感染的危险因素;采用SPSS19.0软件进行统计分析。结果干预后患者的体温、中性粒细胞比例、白细胞总数以及PCT值明显低于干预前,差异有统计学意义(P0.05);单因素分析显示,年龄、吸烟史、合并基础疾病、麻醉时间、插管途径、插管部位、插管深度以及拔管时间与下呼吸道感染的发生具有相关性(P0.05);多因素logistic回归分析显示,年龄、麻醉时间、插管途径、插管部位、插管深度以及拔管时间是患者发生下呼吸道感染的独立危险因素(P0.05)。结论患者气管插管全麻术后均会增加下呼吸道感染风险,临床上应该加强对该危险因素的控制以降低患者发生下呼吸道感染的风险。
[Abstract]:Objective to investigate the risk factors of lower respiratory tract infection in patients undergoing tracheal intubation and general anesthesia. Methods from June 2012 to June 2014, 1013 patients with lower respiratory tract infection after tracheal intubation general anesthesia were selected as study subjects, 60 patients with lower respiratory tract infection were treated with relevant intervention. Body temperature, neutrophil ratio, total leukocyte count and procalcitonin (PCT) were compared before and after intervention. The related factors of lower respiratory tract infection were analyzed, and the risk factors of lower respiratory tract infection were analyzed by multivariate logistic regression analysis, and the statistical analysis was carried out by SPSS19.0 software. Results the body temperature, neutrophil ratio, total leukocyte count and PCT value of patients after intervention were significantly lower than those before intervention (P0.05). Univariate analysis showed that age, smoking history, underlying diseases, anesthesia time, intubation pathway, intubation site, intubation depth and extubation time were correlated with the incidence of lower respiratory tract infection (P0.05). Multivariate logistic regression analysis showed that age, anesthesia time, intubation pathway, intubation site, intubation depth and extubation time were independent risk factors for lower respiratory tract infection (P0.05). Conclusion the risk of lower respiratory tract infection can be increased after tracheal intubation. The risk factors should be controlled in clinic to reduce the risk of lower respiratory tract infection.
【作者单位】：义乌稠州医院麻醉科;
【基金】：浙江省卫生厅基金资助项目(2013KYA192)
【分类号】：R614

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