聚维酮碘预防气管插管细菌寄殖研究

发布时间：2019-02-15 00:03

【摘要】：目的观察使用聚维酮碘溶液降低气管插管全麻患者气管内细菌的污染程度的可行性。方法 100例在气管插管全麻下行择期手术的患者随机分为试验组(n=50)和对照组(n=50),试验组患者术前0.25%聚维酮碘溶液深漱口,同时插入的气管导管均在0.25%的聚维酮碘溶液浸泡过后干燥无菌;对照组患者术前只用0.9%生理盐水深漱口,插入的无菌气管导管未做任何抗菌处理。在麻醉过程中的不同时间点无菌拭子取样,之后细菌计数培养和鉴定。结果含漱后试验组患者口腔内细菌数明显低于对照组(P0.05),并且没有检测到耐甲氧西林金黄色葡萄球菌(MRSA)。拔除气管导管后再次口咽部细菌培养也提示聚维酮碘溶液有持续的抑菌杀菌作用(P0.05),试验组处理方法对于减少口咽部细菌下移、黏附、定植气管内表面更有意义(P0.05)。结论聚维酮碘溶液用作术前口腔护理和气管导管抗菌处理,可有效预防气管内细菌污染。
[Abstract]:Objective to observe the feasibility of using povidone iodine solution to reduce bacterial contamination in tracheal intubation. Methods 100 patients undergoing elective operation under tracheal intubation under general anesthesia were randomly divided into two groups: the experimental group (n = 50) and the control group (n = 50). The patients in the test group were gargled with 0.25% povidone iodine solution before operation. The trachea catheter inserted at the same time was dried and sterile after immersion in 0.25% povidone iodine solution. In the control group, only 0.9% saline deep gargle was used before operation, and the sterile tracheal catheter was not treated with any antimicrobial treatment. The sterile swabs were sampled at different time points during anaesthesia, and then the bacteria were cultured and identified. Results the number of bacteria in oral cavity in the test group after gargling was significantly lower than that in the control group (P0.05), and no methicillin-resistant Staphylococcus aureus (MRSA). Was detected in the test group (P0.05). The culture of bacteria in oropharynx after extubation of trachea catheter also indicated that povidone iodine solution had a continuous bactericidal effect (P0.05). The inner surface of trachea was more significant (P0.05). Conclusion povidone iodine solution can effectively prevent bacterial contamination in trachea as preoperative oral nursing care and tracheal catheter antimicrobial treatment.
【作者单位】：广东省东莞市第五人民医院;
【分类号】：R472.1

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