鹿复合麻醉剂对鹿无创血压、血浆ANP、CGRP及RAAS影响

发布时间：2019-03-15 13:14

【摘要】：为明确鹿复合麻醉剂作用下鹿血压变化与血浆肾素-血管紧张素-醛固酮系统、心钠素、降钙素基因相关肽相关性。试验选取6只健康成年梅花鹿,肌注鹿复合麻醉剂0.04 m L·kg-1,注药前及注药后0、15、30、45、60、75、90及120 min血压监测,并同步采集颈静脉血样测定肾素(PRA)、血管紧张素(AⅡ)、醛固酮(ALD)、心钠素(ANP)和降钙素基因相关肽(CGRP)含量。结果表明,梅花鹿麻醉期血浆中ANP、PRA、AⅡ和ALD含量下降,与对照组相比显著降低(P0.01或P0.05);CGRP含量升高,与对照组相比极显著升高(P0.01);SBP、DBP和MAP显著低于对照组(P0.01)。说明鹿复合麻醉剂引起肾素-血管紧张素-醛固酮系统、心钠素、降钙素基因相关肽变化,参与鹿血压变化调节。
[Abstract]:To investigate the relationship between the changes of blood pressure and plasma renin-angiotensin-aldosterone system, atrial natriuretic peptide and calcitonin gene-related peptide (CGRP) under the action of compound anesthetic in deer. Six healthy adult sika deer were selected for blood pressure monitoring before and after 0. 04 mL kg-1, injection and 0, 15, 30, 45, 60, 75, 90 and 120 min blood pressure monitoring, and renin (PRA), angiotensin (A 鈪，

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