罗哌卡因联合布托啡诺对妇科腹腔镜手术后疼痛影响的对照研究

发布时间：2019-06-02 05:51

【摘要】：目的观察静脉注射布托啡诺联合腹腔内注射罗哌卡因对妇科腹腔镜手术患者术后疼痛的影响。方法将2013年9月~2014年3月80例择期在全身麻醉下行妇科腹腔镜手术患者随机分为观察组(罗哌卡因联合布托啡诺组)和对照组,每组40例。观察组术前30分钟静脉注射布托啡诺20μg/kg,并在气腹结束前向手术创面喷洒0.4%罗哌卡因5 ml,缝合皮肤前向切口局部注射0.4%罗哌卡因5 ml。对照组给予同等量生理盐水。采用视觉模拟评分(visual analogue score,VAS)评价术后2、6、12、24 h的疼痛强度。结果术后2、6、12 h观察组的VAS均低于对照组(2 h:4.1±0.6 vs.6.8±0.8,t=-16.419,P=0.000;6 h:3.2±0.8 vs.7.1±1.5,t=-14.425,P=0.000;12 h:3.4±0.5 vs.6.2±1.9,t=-8.733,P=0.002),术后24 h 2组VAS差异无显著性(3.1±0.8 vs.3.2±0.7,t=-0.723,P=0.472)。结论布托啡诺联合罗哌卡因可显著缓解妇科腹腔镜术后疼痛,且无明显不良反应。
[Abstract]:Objective to observe the effect of intravenous butofenol combined with intraabdominal injection of ropivacaine on postoperative pain in patients undergoing gynecological laparoscopic surgery. Methods from September 2013 to March 2014, 80 patients undergoing gynecological laparoscopic surgery under general anesthesia were randomly divided into observation group (ropivacaine combined with butorphalin group) and control group (n = 40). In the observation group, 20 渭 g / kg, butofenol was injected intravenously 30 minutes before pneumoperitoneum and 0.4% ropivacaine was sprayed with 0.4% ropivacaine 5 ml, to suture the skin and local injection of 0.4% ropivacaine 5 ml. before pneumoperitoneum was completed. The control group was given the same amount of saline. Visual analog score (visual analogue score,VAS) was used to evaluate the pain intensity at 2 h, 6 h, 12 h and 24 h after operation. Results the VAS of the observation group was lower than that of the control group at 2 h, 6 h and 12 h after operation (4. 1 卤0. 6 vs.6.8 卤0.8, t = 16. 419, P < 0. 006 h, 3. 2 卤0. 8 vs.7.1 卤1. 5, t = 14. 425, P 鈮，

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