肾盂绒毛状腺瘤1例并文献复习

发布时间：2018-03-03 03:01

本文选题：肾盂肿瘤　切入点：腺瘤　出处：《临床与实验病理学杂志》2016年05期 　论文类型：期刊论文

【摘要】：目的探讨肾盂绒毛状腺瘤的临床病理学特征、组织学发生、诊断、鉴别诊断及预后。方法回顾性分析1例肾盂绒毛状腺瘤,并复习相关文献。结果患者女性,58岁,因卵巢肿瘤复发多次行手术治疗,此次因腰部疼痛、腹部CT示左肾无功能,遂行肾切除术。患者术后死于放射治疗并发症。眼观:肾盂移行上皮完全肠化,呈乳头状生长,肿瘤细胞异型性不明显。免疫表型:瘤细胞弥漫表达CK7、CEA和EMA,部分表达Villin和CDX2;不表达CK20和PAX-8;Ki-67增殖指数约5%。结论原发于肾盂的绒毛状腺瘤罕见,确诊主要依靠病理学形态及免疫表型。单纯的绒毛状腺瘤预后较好,而该例患者因卵巢肿瘤复发导致预后差。
[Abstract]:Objective to investigate the clinicopathological features, histogenesis, diagnosis, differential diagnosis and prognosis of renal pelvis villous adenoma. Because of the recurrence of ovarian tumor, many times surgery was performed. Because of the pain in the waist, abdominal CT showed that the left kidney had no function, and the patient underwent nephrectomy. The patient died of complications of radiotherapy after operation. Eye view: the transitional epithelium of the renal pelvis became completely intestinal and grew papillary. Immunophenotype: CK7CEA and EMA were expressed in the tumor cells, and Villin and CDX2 were partially expressed in the tumor cells. The proliferative index of CK20 and PAX-8KI-67 was about 5.Conclusion the primary villous adenoma in renal pelvis is rare. The prognosis of simple villous adenoma was good, but the prognosis of this patient was poor due to the recurrence of ovarian tumor.
【作者单位】：南京大学医学院附属鼓楼医院病理科;江苏泗洪分金亭医院儿科;
【分类号】：R737.11

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