重型颅脑损伤患者尿路感染病原学特点及危险因素分析

发布时间：2018-05-03 22:37

本文选题：重型颅脑损伤 + 尿路感染　；参考：《中华医院感染学杂志》2017年20期

【摘要】：目的分析重型颅脑损伤(SBI)患者尿路感染病原菌分布及危险因素分析。方法选取医院2014年8月-2016年8月收治的SBI患者156例作为研究对象,对所有纳入患者的术后尿路感染情况进行观察和分析,对与患者术后尿路感染发生相关的因素进行研究和分析,对发生尿路感染患者尿液样本中的病原菌进行检测和分析。结果术后发生尿路感染患者51例,感染率32.69%,感染患者以发热、尿路刺激征、尿道口瘙痒为主要临床体征;共分离病原菌72株,其中革兰阴性菌35株占48.61%,以大肠埃希菌为主;革兰阳性菌11株占15.28%,以粪肠球菌为主,真菌26株占36.11%,以白色假丝酵母菌为主;合并糖尿病、GCS评分、留置导尿管时间是SBI患者发生尿路感染的独立危险因素(P0.05)。结论 SBI术后尿路感染的相关因素、临床体征和病原菌分布具有特征性,给予充分的重视和有效的诊治,以提高SBI患者救治成功率和医院感染工作的效果。
[Abstract]:Objective to analyze the distribution and risk factors of urinary tract infection in patients with severe craniocerebral injury (SBI). Methods 156 patients with SBI admitted from August 2014 to August 2016 were selected as the study subjects, and the postoperative urinary tract infection of all the patients involved were observed and analyzed. The factors related to postoperative urinary tract infection were studied and analyzed. The pathogenic bacteria in urine samples of patients with urinary tract infection were detected and analyzed. Results there were 51 patients with urinary tract infection after operation, the infection rate was 32.69. The main clinical signs were fever, urinary tract irritation sign and urinal pruritus. 72 strains of pathogenic bacteria were isolated, of which 35 strains were Gram-negative bacteria (48.61%), mainly Escherichia coli. There were 11 Gram-positive bacteria (15.28%), mainly Enterococcus faecalis, 26 fungi (36.11), and most of them were Candida albicans. GCS score and indwelling catheter time were the independent risk factors of urinary tract infection in SBI patients (P 0.05). Conclusion the related factors, clinical signs and pathogenic bacteria distribution of urinary tract infection after SBI are characteristic, which should be paid enough attention to and effective diagnosis and treatment, in order to improve the success rate of treatment of SBI patients and the effect of nosocomial infection.
【作者单位】：南通大学附属医院神经外科;
【基金】：国家自然科学基金资助项目(81471256) 南通市科学技术局基金资助项目(MS22016017)
【分类号】：R651.15;R691.3

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