166例肾移植患者术后医院感染病原菌的分布及耐药性分析

发布时间：2018-06-10 05:12

本文选题：肾移植 + 医院感染　；参考：《中国现代医学杂志》2017年13期

【摘要】：目的了解肾移植患者术后医院感染病原菌的分布、标本来源及耐药性,为预防和合理使用抗菌药物有效控制肾移植术后患者医院感染提供依据。方法回顾分析郑州人民医院2013年1月-2015年12月肾移植患者术后送检的各类标本中分离出的病原菌的分布、标本来源及耐药性,细菌的鉴定和药物敏感性试验采用法国生物梅里埃公司VITEK 2 Compact全自动细菌鉴定药敏分析仪。结果共分离出204株病原菌,其中,革兰阴性菌144株,革兰阳性菌48株,真菌12株,分别占70.588%、23.529%和5.882%;主要来源于中段尿,其次是痰液和伤口分泌物,依次占39.216%、27.451%和13.725%;主要革兰阴性菌对多数常用抗菌药物产生了高度耐药,主要革兰阳性菌金黄色葡萄球菌的耐药率更高,MRSA阳性率高达58.333%,未发现耐万古霉素和利奈唑胺的金黄色葡萄球菌和屎肠球菌。结论肾移植患者术后医院感染的发生率较高,泌尿系统和呼吸系统是其主要易感部位,革兰阴性菌是主要病原菌,且对多数抗菌药物呈现高度耐药,所以要加强细菌监测和药物敏感性试验,有效预防和控制医院感染的发生。
[Abstract]:Objective to understand the distribution, source and drug resistance of the pathogenic bacteria of hospital infection after renal transplantation, and to provide the basis for the effective control of the hospital infection after renal transplantation for prevention and rational use of antibiotics. Methods a retrospective analysis was made in the various specimens of the renal transplant patients in the Zhengzhou people's Hospital in December -2015 January 2013. The distribution of pathogenic bacteria, the source of the specimen and the drug resistance, the identification of bacteria and the drug sensitivity test adopted the VITEK 2 Compact automatic bacterial identification analyzer of the French biier company. The results were divided into 204 pathogenic bacteria, including 144 Gram-negative bacteria, 48 Gram-positive bacteria and 12 fungi, accounting for 70.588%, 23.529% and 5.882, respectively. %, mainly from middle urine, followed by sputum and wound secretions, which accounted for 39.216%, 27.451% and 13.725%, and major Gram-negative bacteria were highly resistant to most of the commonly used antibiotics. The main gram positive bacteria, Staphylococcus aureus, were higher, MRSA positive rate was 58.333%, and no vancomycin and linezolid resistant gold was found. Staphylococcus aureus and Enterococcus faecium. Conclusion the incidence of hospital infection in renal transplant patients is higher, urinary system and respiratory system are the main susceptible parts. Gram-negative bacteria are the main pathogens and are highly resistant to most antibiotics. Therefore, we should strengthen the monitoring of bacteria and drug sensitivity test, effectively prevent and control medical treatment. The incidence of nosocomial infection.
【作者单位】：郑州人民医院检验科;
【分类号】：R446.5;R699.2

【相似文献】