固精麦斯哈片联合天然维生素E治疗特发性弱精子症的临床研究

发布时间：2018-07-01 09:22

本文选题：弱精子症 + 固精麦斯哈片　；参考：《中华男科学杂志》2017年12期

【摘要】：目的:研究固精麦斯哈片联合天然维生素E治疗特发性弱精子症的临床效果。方法:纳入2015年1月至2016年1月门诊135例弱精子症患者。随机分为两组,治疗组患者72例,年龄22~44岁,平均年龄33.6岁;对照组患者63例,年龄21~43岁,平均年龄32.8岁。治疗组服用固精麦斯哈片(每次6片,每日2次)和天然维生素E(每次100 mg,每日2次),对照组服用天然维生素E(每次100 mg,每日2次),连续服用30 d为1个疗程,总共3个疗程。治疗前及治疗90 d后通过对精子总活力(PR+NP)、精子前向运动率(PR)和配偶妊娠情况比较,评估其临床有效性。结果:治疗组和对照组在治疗前,精液中PR+NP、PR分别为(25.23±5.57)%和(17.53±5.78)%、(26.05±6.77)%和(15.11±6.55)%,数据无统计学差异(P0.05)。治疗组治疗90 d后精液中PR+NP、PR分别为(48.73±8.66)%、(32.77±6.04)%,与治疗前比较,差异具有统计学意义(P0.05);对照组治疗90 d后精液中PR+NP、PR分别为(36.54±8.09)%、(26.99±6.87)%,与治疗前比较同样具有统计学意义(P0.05)。但是治疗组精液中PR+NP、PR改善明显优于对照组,差异具有统计学意义(P0.05)。临床疗效上,治疗组总有效率(73.85%)明显高于对照组(54.55%),两组间差异具有统计学意义(P0.05)。在整个治疗过程中,两组均无不良反应。结论:固精麦斯哈片联合天然维生素E用药对不明原因弱精子症有较好的临床效果。
[Abstract]:Objective: to study the clinical effect of treating idiopathic asthenospermia with Gu Jing Maisha tablet combined with natural vitamin E. Methods: 135 patients with asthenospermia were enrolled from January 2015 to January 2016. Two groups were randomly divided into two groups: the treatment group (72 cases) with an average age of 33.6 years (22 ~ 44 years) and the control group (63 cases) with an average age of 32.8 years (21 ~ 43 years). The treatment group (6 tablets, twice a day) and the control group (100 mg / day, 2 times a day), the control group (100 mg / day, 2 times a day), continuously take 30 days as a course of treatment, a total of 3 courses. The clinical efficacy of total sperm motility (PR NP), sperm forward motility rate (PR) and spouse pregnancy were evaluated before and 90 days after treatment. Results: before treatment, PR NPP PR in semen was (25.23 卤5.57)%, (17.53 卤5.78), (26.05 卤6.77)% and (15.11 卤6.55) in treatment group and control group, respectively (P0.05). The PR NPPR in semen of the treatment group was (48.73 卤8.66) and (32.77 卤6.04) respectively after 90 days of treatment, which was significantly higher than that before treatment (P0.05), while that in the control group was (36.54 卤8.09), (26.99 卤6.87) after 90 days of treatment, which was also statistically significant compared with that before treatment (P0.05). But the improvement of PR NPN PR in semen in treatment group was significantly better than that in control group (P0.05). The total effective rate in the treatment group (73.85%) was significantly higher than that in the control group (54.55%), and the difference between the two groups was statistically significant (P0.05). There were no adverse reactions in both groups during the whole course of treatment. Conclusion: Gujing Maisha tablet combined with natural vitamin E has a better clinical effect on unexplained asthenospermia.
【作者单位】：第三军医大学大坪医院野战外科研究所泌尿外科;
【分类号】：R698.2

【相似文献】