性激素及精浆生化检测指标与精液液化时间的相关性
发布时间:2018-07-22 16:59
【摘要】:目的:通过探讨精液液化异常患者性激素水平及生殖管道各附属腺体(附睾、精囊、前列腺等)功能状态,系统分析影响精液液化时间的相关因素,为精液液化异常的个体化诊治提供临床依据。方法:纳入符合入组标准的育龄男性患者152例,根据精液液化时间将患者分为两组:液化异常组(精液液化时间60 min组)和液化正常组(液化时间为≤60 min组)。测定精液常规参数、性激素5项及附属腺体功能指标精浆生化等。一是运用T检验比较两组间生殖管道各附属腺体功能状态(p H值、中性α-糖苷酶、果糖、精浆锌和柠檬酸)及性激素水平(FSH、LH、PRL、T和E2)是否存有显著差异;二是运用Logistic回归分析检测上述指标与精液液化能力的相关性。结果:精液液化异常组(52例)与正常组(100例)相比,两组间精液p H值(7.47±0.13 vs 7.32±0.18)、柠檬酸(51.12±12.95 vs 83.11±33.46)和FSH(4.40±1.03 vs 4.85±1.50)差异有统计学意义(P0.05),余差异无统计学意义。相关性回归分析显示,精液液化能力与精囊腺功能指标果糖(OR=2.644)、前列腺功能指标柠檬酸(OR=0.922)、血清T(OR=0.611)及E2(OR=1.029)水平存在相关性(P0.05),而与分析指标中的其他因素无明显关系。结论:精液的液化能力与两腺体(前列腺/精囊腺)功能状态及两激素水平(T/E2)存在相关性,临床诊疗精液液化异常患者时,可根据具体致病因素给予区别化针对性治疗。
[Abstract]:Objective: to investigate the levels of sex hormones and the functional status of the accessory glands (epididymis seminal vesicle prostate etc.) in patients with abnormal semen liquefaction and to systematically analyze the related factors affecting semen liquefaction time. To provide clinical basis for individual diagnosis and treatment of abnormal semen liquefaction. Methods: according to semen liquefaction time, 152 male patients of childbearing age were divided into two groups: abnormal liquefaction group (semen liquefaction time 60 min) and normal liquefaction group (liquefaction time 鈮,
本文编号:2138146
[Abstract]:Objective: to investigate the levels of sex hormones and the functional status of the accessory glands (epididymis seminal vesicle prostate etc.) in patients with abnormal semen liquefaction and to systematically analyze the related factors affecting semen liquefaction time. To provide clinical basis for individual diagnosis and treatment of abnormal semen liquefaction. Methods: according to semen liquefaction time, 152 male patients of childbearing age were divided into two groups: abnormal liquefaction group (semen liquefaction time 60 min) and normal liquefaction group (liquefaction time 鈮,
本文编号:2138146
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